ArticleBMC infectious diseases2020
Detection of Listeria monocytogenes in a patient with meningoencephalitis using next-generation sequencing: a case report.
Article in BMC infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- The added value of metagenomic next-generation sequencing in central nervous system infections: a systematic review of case reports.Infection · 2025Pooled it
- Article
- Metagenomic Next-Generation Sequencing for Brain Abscess: Improved Pathogen Detection, Targeted Antimicrobial Therapy, and Association with Fewer Surgical Interventions.Infection and drug resistance · 2026Article
- A Case Report of Meningitis with Possible Coinfection byCase reports in critical care · 2026Article
- Metagenomic Sequencing for Diagnosing Listeria-Induced Rhombencephalitis in Patient and Contaminated Cheese Samples: A Case Report.International journal of molecular sciences · 2025Article
- Confirmation of Tuberculous Meningitis Using Metagenomic Next-Generation Sequencing: A Case Report.Infection and drug resistance · 2025Article
- Prevalence and Antimicrobial Resistance ofFoods (Basel, Switzerland) · 2024Article
- Clinical characteristics and prognosis of pediatricMicrobiology spectrum · 2024Article
- Article
- Next-generation sequencing: what are the needs in routine clinical microbiology? A survey among clinicians involved in infectious diseases practice.Frontiers in medicine · 2023Article
- Bacterial meningitis in Africa.Frontiers in neurology · 2023Review
- Clinical Characteristics and Treatment ofInfection and drug resistance · 2023Article
- The Clinical Characteristics, Diagnostic Methods, Treatment, and Outcomes ofInfection and drug resistance · 2023Article
- A case report of diagnosis and dynamic monitoring ofOpen life sciences · 2023Article
- Treatment failure in a patient infected withWorld journal of clinical cases · 2022Article
- Possible role of low dose dexamethasone administration in listeria monocytogenes meningoencephalitis: A case series.Biomedical reports · 2022Article
- Brainstem abscesses caused byWorld journal of clinical cases · 2022Article
- Direct Metagenomic Diagnosis of Community-Acquired Meningitis: State of the Art.Frontiers in microbiology · 2022Review
- Recurrent Pneumonia With Tuberculosis andFrontiers in medicine · 2022Article
- A Retrospective Study of Rare Listeria Meningoencephalitis in Immunocompetent Children in China.Frontiers in neurology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundListeria monocytogenes (L. monocytogenes) is a facultative intracellular bacterial pathogen which can invade different mammalian cells and reach to the central nervous system (CNS), leading to meningoencephalitis and brain abscesses. In the diagnosis of L. monocytogenes meningoencephalitis (LMM), the traditional test often reports negative owing to the antibiotic treatment or a low number of bacteria in the cerebrospinal fluid. To date, timely diagnosis and accurate treatment remains a challenge for patients with listeria infections. CASE PRESENTATION: We present the case of a 66-year-old woman whose clinical manifestations were suspected as tuberculous meningoencephalitis, but the case was finally properly diagnosed as LMM by next-generation sequencing (NGS). The patient was successfully treated using a combined antibacterial therapy, comprising ampicillin and trimethoprim-sulfamethoxazole.
conclusionTo improve the sensitivity of LMM diagnosis, we used NGS for the detection of L. monocytogenes. Hence, the clinical utility of this approach can be very helpful since it provides quickly and trust results.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.