Evidence map›Paper›PMID 33003979›Full record

ArticleJournal of neurotrauma2021

Association of Head Impact Exposure with White Matter Macrostructure and Microstructure Metrics.

Benjamin L Brett, Kevin M Koch, L Tugan Muftuler, Matthew Budde, Michael A McCrea, Timothy B Meier

Open access · greenAbstract read
In one paragraph

Article in Journal of neurotrauma, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Benjamin L BrettDepartment of Neurosurgery, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Kevin M KochCenter for Neurotrauma Research, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
L Tugan MuftulerDepartment of Neurosurgery, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Matthew BuddeDepartment of Neurosurgery, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Michael A McCreaDepartment of Neurosurgery, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Timothy B MeierDepartment of Neurosurgery, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Medical College of Wisconsin · US

Funding

Clinical and Translational Science AwardUL1TR001436 · NCATS · MEDICAL COLLEGE OF WISCONSIN · PI FREED, JULIE K · 2015 to 2025
$47.5M
The role of neuroactive kynurenine metabolites in the chronic sequelae of concussion and contact sport exposureR01NS102225 · NINDS · MEDICAL COLLEGE OF WISCONSIN · PI MEIER, TIMOTHY B. · 2018 to 2022
$1.8M
NCATS NIH HHS UL1 TR001436NINDS NIH HHS L30 NS113158NINDS NIH HHS R01 NS102225
6 · The paper itself

Abstract

Prior studies have reported white matter abnormalities associated with a history of cumulative concussion and/or repetitive head impacts (RHI) in contact sport athletes. Growing evidence suggests these abnormalities may begin as more subtle changes earlier in life in active younger athletes. We investigated the relationship between prior concussion and contact sport exposure with multi-modal white matter microstructure and macrostructure using magnetic resonance imaging. High school and collegiate athletes (

Indexed as

AdolescentAthletic InjuriesBrain ConcussionCraniocerebral TraumaDiffusion Tensor ImagingHumansMaleNeuroimagingWhite MatterYoung Adultconcussiondiffusion kurtosis imagingdiffusion tensor imagingquantitative susceptibility mappingrepetitive head impacts

Identifiers

PMID33003979
PMCPMC7875606
OpenAlexW3091598962

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.