Evidence map›Paper›PMID 33003611›Full record

ArticleInternational journal of molecular sciences2020

The Interaction of Innate and Adaptive Immunity and Stabilization of Mast Cell Activation in Management of Infusion Related Reactions in Patients with Fabry Disease.

Renuka P Limgala, Jaqueline Fikry, Vasudha Veligatla, Ozlem Goker-Alpan

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Progress and Challenges in the Treatment of Fabry Disease.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2025
    Review
  8. Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Renuka P LimgalaTranslational Research Unit, Lysosomal and Rare Disorders Research and Treatment Center, Fairfax, VA 22030, USA.ORCID 0000-0001-6957-6284
Jaqueline FikryTranslational Research Unit, Lysosomal and Rare Disorders Research and Treatment Center, Fairfax, VA 22030, USA.
Vasudha VeligatlaTranslational Research Unit, Lysosomal and Rare Disorders Research and Treatment Center, Fairfax, VA 22030, USA.
Ozlem Goker-AlpanTranslational Research Unit, Lysosomal and Rare Disorders Research and Treatment Center, Fairfax, VA 22030, USA.ORCID 0000-0003-4758-6793
Lysosomal and Rare Disorders Research and Treatment Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fabry disease (FD) is an X-linked lysosomal disorder caused by mutations in

Indexed as

Adaptive ImmunityAdolescentAdultalpha-GalactosidaseChildEnzyme Replacement TherapyFabry DiseaseHumansImmunity, InnateImmunoglobulin EInflammationInjection Site ReactionIsoenzymesMaleMast CellsMiddle Agedagalsidase alfaalpha-GalactosidaseImmunoglobulin EIsoenzymesRecombinant Proteinsagalsidaseenzyme replacement therapyFabry diseaseinfusion-related reactions

Identifiers

PMID33003611
PMCPMC7583043
OpenAlexW3090709607

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.