Evidence map›Paper›PMID 33003609›Full record

ReviewPharmaceutics2020

Hyaluronic Acid Nanoparticles as Nanomedicine for Treatment of Inflammatory Diseases.

N Vijayakameswara Rao, Jun Gi Rho, Wooram Um, Pramod Kumar Ek, Van Quy Nguyen, Byeong Hoon Oh, Wook Kim, Jae Hyung Park

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Trial
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  9. Review
  10. Hyaluronic Acid in Nanopharmaceuticals: An Overview.Current issues in molecular biology · 2024
    Review
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  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

N Vijayakameswara RaoSchool of Chemical Engineering, Sungkyunkwan University, Suwon 16419, Korea.ORCID 0000-0001-8534-7158
Jun Gi RhoDepartment of Molecular Science & Technology, Ajou University, Suwon 16499, Korea.
Wooram UmSchool of Chemical Engineering, Sungkyunkwan University, Suwon 16419, Korea.ORCID 0000-0003-2479-0783
Pramod Kumar EkSchool of Chemical Engineering, Sungkyunkwan University, Suwon 16419, Korea.
Van Quy NguyenSchool of Chemical Engineering, Sungkyunkwan University, Suwon 16419, Korea.ORCID 0000-0002-5952-0700
Byeong Hoon OhSchool of Chemical Engineering, Sungkyunkwan University, Suwon 16419, Korea.
Wook KimDepartment of Molecular Science & Technology, Ajou University, Suwon 16499, Korea.ORCID 0000-0002-7701-4684
Jae Hyung ParkSchool of Chemical Engineering, Sungkyunkwan University, Suwon 16419, Korea.

Funding

National Research Foundation of Korea 20100027955National Research Foundation of Korea 2018R1A2B3006080National Research Foundation of Korea 2019M3E5D5066525National Research Foundation of Korea 2019R1A2B5B03100464National Research Foundation of Korea 2019R1A6A1A11051471
6 · The paper itself

Abstract

Owing to their unique biological functions, hyaluronic acid (HA) and its derivatives have been explored extensively for biomedical applications such as tissue engineering, drug delivery, and molecular imaging. In particular, self-assembled HA nanoparticles (HA-NPs) have been used widely as target-specific and long-acting nanocarriers for the delivery of a wide range of therapeutic or diagnostic agents. Recently, it has been demonstrated that empty HA-NPs without bearing any therapeutic agent can be used therapeutically for the treatment of inflammatory diseases via modulating inflammatory responses. In this review, we aim to provide an overview of the significant achievements in this field and highlight the potential of HA-NPs for the treatment of inflammatory diseases.

Indexed as

atherosclerosisdrug conjugateshyaluronic acidinflammatory diseasespolymeric nanoparticlestargeted-therapytumor-targetingtype 2 diabetes

Identifiers

PMID33003609
PMCPMC7600604

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.