Evidence map›Paper›PMID 33003597›Full record

ArticleMarine drugs2020

Therapeutic Potential of (-)-Agelamide D, a Diterpene Alkaloid from the Marine Sponge

Changhoon Choi, Yeonwoo Cho, Arang Son, Sung-Won Shin, Yeon-Ju Lee, Hee Chul Park

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Changhoon ChoiDepartment of Radiation Oncology, Samsung Medical Center, Seoul 06351, Korea.ORCID 0000-0002-2847-1168
Yeonwoo ChoMarine Natural Products Chemistry Laboratory, Korea Institute of Ocean Science and Technology, 385 Haeyangro, Busan 49111, Korea.
Arang SonDepartment of Radiation Oncology, Samsung Medical Center, Seoul 06351, Korea.
Sung-Won ShinDepartment of Radiation Oncology, Samsung Medical Center, Seoul 06351, Korea.
Yeon-Ju LeeMarine Natural Products Chemistry Laboratory, Korea Institute of Ocean Science and Technology, 385 Haeyangro, Busan 49111, Korea.ORCID 0000-0003-4814-943X
Hee Chul ParkDepartment of Radiation Oncology, Samsung Medical Center, Seoul 06351, Korea.ORCID 0000-0003-0385-9681
Samsung Medical Center · KRKorea Institute of Ocean Science and Technology · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiation therapy (RT) is an effective local treatment for unresectable hepatocellular carcinoma (HCC), but there are currently no predictive biomarkers to guide treatment decision for RT or adjuvant systemic drugs to be combined with RT for HCC patients. Previously, we reported that extracts of the marine sponge

Indexed as

AgelasAnimalsCarcinoma, HepatocellularCell Line, TumorDiterpene AlkaloidsHumansLiver NeoplasmsMaleMiceMice, Inbred BALB CMice, NudeRadiation-Sensitizing AgentsUnfolded Protein ResponseXenograft Model Antitumor AssaysDiterpene AlkaloidsRadiation-Sensitizing Agentsactivating transcription factor 4 (ATF4)(−)-agelamide Dhepatocellular carcinomaradiation therapyunfolded protein response (UPR)

Identifiers

PMID33003597
PMCPMC7600430
OpenAlexW3089557374

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.