Evidence map›Paper›PMID 33003574›Full record

ArticleJournal of clinical medicine2020

Non-Alcoholic Fatty Liver Disease Markers Associated with Fasting Serum Insulin and Urinary Albumin Excretion Independent of Fasting Plasma Glucose.

Shuichi Katoh, Markku Peltonen, Mikio Zeniya, Yoichi Sakamoto, Kazunori Utsunomiya, Rimei Nishimura, Jaakko Tuomilehto

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 84% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Shuichi KatohDivision of Diabetes, Metabolism & Endocrinology, The Jikei University School of Medicine, 3-25-8 Nishishimbashi, Minato-ku, Tokyo 105-8461, Japan.
Markku PeltonenPublic Health Promotion Unit, Finnish Institute for Health and Welfare, Mannerheimintie 166, FI-00271 Helsinki, Finland.
Mikio ZeniyaGastroenterology, Akasaka Sanno Medical Center, 4-1-26W Akasaka, Minato-ku, Tokyo 107-8402, Japan.
Yoichi SakamotoJikei University Harumi Triton Clinic, The Jikei University School of Medicine, 3-25-8 Nishishimbashi, Minato-ku, Tokyo 105-8461, Japan.
Kazunori UtsunomiyaDepartment of Health-Care Center, The Jikei University School of Medicine, 3-25-8 Nishishimbashi, Minato-ku, Tokyo 105-8461, Japan.
Rimei NishimuraDivision of Diabetes, Metabolism & Endocrinology, The Jikei University School of Medicine, 3-25-8 Nishishimbashi, Minato-ku, Tokyo 105-8461, Japan.
Jaakko TuomilehtoPublic Health Promotion Unit, Finnish Institute for Health and Welfare, Mannerheimintie 166, FI-00271 Helsinki, Finland.
Jikei University School of Medicine · JPFinnish Institute for Health and Welfare · FIKing Abdulaziz University · SASanno Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe examined the association between non-alcoholic fatty liver disease (NAFLD) markers and fasting serum immunoreactive insulin (FIRI) and urinary albumin excretion (UAE). SUBJECTS AND

methodsThis study comprised Periods I and II from January 2007 to May 2009, and from June 2009 to December 2011, respectively. After excluding people with ethanol intake ≥210 g/week in men and ≥140 g/week in women, 961 people (613 men, 348 women; mean age: 44 years) were included. We evaluated the fatty liver using ultrasonography score (FLUS) and measured liver enzymes.

resultsThe mean observation period was 25 ± 9 months. We stratified people into two groups by fasting plasma glucose (FPG) in Period I. The cutoff point between the lower FPG and higher FPG was 100 mg/dL. In regression analysis, serum alanine aminotransferase (ALT) (

conclusionsSome NAFLD markers were associated with FIRI and UAE independently of fasting plasma glucose.

Indexed as

diabetesfasting serum insulinimpaired fasting glucosenon-alcoholic fatty liver diseaseserum alanine aminotransferaseurinary albumin excretion

Identifiers

PMID33003574
PMCPMC7650561
OpenAlexW3091460742

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.