Evidence map›Paper›PMID 33003551›Full record

ArticleCancers2020

Investigating Radiotherapy Response in a Novel Syngeneic Model of Prostate Cancer.

Charles M Haughey, Debayan Mukherjee, Rebecca E Steele, Amy Popple, Lara Dura-Perez, Adam Pickard, Mehjabin Patel, Suneil Jain, Paul B Mullan, Rich Williams and 7 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Prostate Cancer and the Mevalonate Pathway.International journal of molecular sciences · 2024
    Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Charles M HaugheyPatrick G Johnston Centre for Cancer Research, Queen's University, Belfast BT9 7AE, UK.
Debayan MukherjeeTargeted Therapy Group, Division of Cancer Sciences, Faculty of Biology Medicine and Health, The University of Manchester, Manchester M13 9PL, UK.ORCID 0000-0002-6356-0684
Rebecca E SteelePatrick G Johnston Centre for Cancer Research, Queen's University, Belfast BT9 7AE, UK.ORCID 0000-0003-4746-7348
Amy PoppleTargeted Therapy Group, Division of Cancer Sciences, Faculty of Biology Medicine and Health, The University of Manchester, Manchester M13 9PL, UK.
Lara Dura-PerezPatrick G Johnston Centre for Cancer Research, Queen's University, Belfast BT9 7AE, UK.
Adam PickardPatrick G Johnston Centre for Cancer Research, Queen's University, Belfast BT9 7AE, UK.ORCID 0000-0001-9757-143X
Mehjabin PatelTargeted Therapy Group, Division of Cancer Sciences, Faculty of Biology Medicine and Health, The University of Manchester, Manchester M13 9PL, UK.
Suneil JainPatrick G Johnston Centre for Cancer Research, Queen's University, Belfast BT9 7AE, UK.
Paul B MullanPatrick G Johnston Centre for Cancer Research, Queen's University, Belfast BT9 7AE, UK.
Rich WilliamsPatrick G Johnston Centre for Cancer Research, Queen's University, Belfast BT9 7AE, UK.
Pedro OliveiraThe Christie Hospital Foundation Trust, Manchester M20 4BX, UK.
Niamh E BuckleyPatrick G Johnston Centre for Cancer Research, Queen's University, Belfast BT9 7AE, UK.
Jamie HoneychurchTargeted Therapy Group, Division of Cancer Sciences, Faculty of Biology Medicine and Health, The University of Manchester, Manchester M13 9PL, UK.
Simon S McDadePatrick G Johnston Centre for Cancer Research, Queen's University, Belfast BT9 7AE, UK.ORCID 0000-0002-3024-4773
Timothy IllidgeTargeted Therapy Group, Division of Cancer Sciences, Faculty of Biology Medicine and Health, The University of Manchester, Manchester M13 9PL, UK.
Ian G MillsPatrick G Johnston Centre for Cancer Research, Queen's University, Belfast BT9 7AE, UK.ORCID 0000-0001-5347-5083
Sharon L EddiePatrick G Johnston Centre for Cancer Research, Queen's University, Belfast BT9 7AE, UK.ORCID 0000-0002-6119-0480
Queen's University Belfast · GBUniversity of Manchester · GBThe Christie Hospital · GB

Funding

Breast Cancer Now 2012MAYSF122Cancer Research UK 28280Cancer Research UK A17737Cancer Research UK C431/A28280Prostate Cancer UK PCUK PG13-021
6 · The paper itself

Abstract

The prostate cancer (PCa) field lacks clinically relevant, syngeneic mouse models which retain the tumour microenvironment observed in PCa patients. This study establishes a cell line from prostate tumour tissue derived from the

Indexed as

myeloid-derived suppressor cellspreclinical modellingprostate cancerradiotherapysyngeneic modeltumour microenvironment

Identifiers

PMID33003551
PMCPMC7599844
OpenAlexW3091536761

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.