Evidence map›Paper›PMID 33003546›Full record

ArticleCancers2020

The RECAP Test Rapidly and Reliably Identifies Homologous Recombination-Deficient Ovarian Carcinomas.

Lise M van Wijk, Sylvia Vermeulen, Matty Meijers, Manuela F van Diest, Natalja T Ter Haar, Marthe M de Jonge, Nienke Solleveld-Westerink, Tom van Wezel, Dik C van Gent, Judith R Kroep and 4 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Functional Homologous Recombination Assay on FFPE Specimens of Advanced High-Grade Serous Ovarian Cancer Predicts Clinical Outcomes.Clinical cancer research : an official journal of the American Association for Cancer Research · 2023
    Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Lise M van WijkDepartment of Human Genetics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.ORCID 0000-0002-3004-5002
Sylvia VermeulenDepartment of Human Genetics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Matty MeijersDepartment of Human Genetics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Manuela F van DiestDepartment of Human Genetics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.ORCID 0000-0002-9040-8418
Natalja T Ter HaarDepartment of Pathology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Marthe M de JongeDepartment of Pathology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Nienke Solleveld-WesterinkDepartment of Pathology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Tom van WezelDepartment of Pathology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.ORCID 0000-0001-5773-7730
Dik C van GentDepartment of Molecular Genetics, Erasmus MC, 3000 CA Rotterdam, The Netherlands.ORCID 0000-0003-1473-8148
Judith R KroepDepartment of Medical Oncology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Tjalling BosseDepartment of Pathology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Katja N GaarenstroomDepartment of Gynecology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Harry VrielingDepartment of Human Genetics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Maaike P G VreeswijkDepartment of Human Genetics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.ORCID 0000-0003-4068-9271
Leiden University Medical Center · NLErasmus MC · NL

Funding

Dutch Cancer Society/Alpe d'HuZes EMCR 2014-7048
6 · The paper itself

Abstract

Recent studies have shown that the efficacy of PARP inhibitors in epithelial ovarian carcinoma (EOC) is related to tumor-specific defects in homologous recombination (HR) and extends beyond

Indexed as

BRCA1BRCA2epithelial ovarian carcinomahomologous recombination deficiencyRAD51RECAP test

Identifiers

PMID33003546
PMCPMC7650677
OpenAlexW3090216282

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.