Evidence map›Paper›PMID 33003405›Full record

ArticleMolecules (Basel, Switzerland)2020

Drug Administration Routes Impact the Metabolism of a Synthetic Cannabinoid in the Zebrafish Larvae Model.

Yu Mi Park, Markus R Meyer, Rolf Müller, Jennifer Herrmann

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

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  14. Zebrafish: An Attractive Model to StudyPharmaceuticals (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Yu Mi ParkDepartment of Microbial Natural Products, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy, Saarland University, Campus E8 1, 66123 Saarbrücken, Germany.
Markus R MeyerDepartment of Experimental and Clinical Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, Center for Molecular Signaling (PZMS), Saarland University, 66421 Homburg, Germany.
Rolf MüllerDepartment of Microbial Natural Products, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy, Saarland University, Campus E8 1, 66123 Saarbrücken, Germany.
Jennifer HerrmannDepartment of Microbial Natural Products, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy, Saarland University, Campus E8 1, 66123 Saarbrücken, Germany.ORCID 0000-0003-3398-9938
German Center for Infection Research · DEKIST Europe · DESaarland University · DE

Funding

KIST Europe Basic Fund Signature Research, Project #12001
6 · The paper itself

Abstract

Zebrafish (

Indexed as

Models, BiologicalAnimalsCannabinoidsCell LineDrug Administration RoutesHumansLarvaMetabolic Detoxication, Phase IMetabolic Detoxication, Phase IIMetabolic Networks and PathwaysMetabolomeSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationZebrafishCannabinoids3R principleadministration routedrug metabolism and pharmacokinetics (DMPK)HepaRG cellsmass spectrometry imaging (MSI)metabolismmethyl 2-(1-(5-fluoropentyl)-1H-pyrrolo [2,3-b]pyridine-3-carboxamido)-3,3-dimethylbutanoate (7′N-5F-ADB)microinjectionsynthetic cannabinoidzebrafish larvae model

Identifiers

PMID33003405
PMCPMC7582563
OpenAlexW3091140219

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.