Evidence map›Paper›PMID 33003371›Full record

ArticleCells2020

Hypoxia Promotes Mitochondrial Complex I Abundance via HIF-1α in Complex III and Complex IV Eficient Cells.

Amy Saldana-Caboverde, Nadee Nissanka, Sofia Garcia, Anne Lombès, Francisca Diaz

Open access · goldAbstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Amy Saldana-CaboverdeDepartment of Neurology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.ORCID 0000-0001-9145-4515
Nadee NissankaDepartment of Neurology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.ORCID 0000-0002-4639-7192
Sofia GarciaDepartment of Neurology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Anne LombèsInstitut Cochin, Unité U1016, INSERM, UMR 8104, CNRS, Université Paris 5, F-75014 Paris, France.ORCID 0000-0002-9064-0399
Francisca DiazDepartment of Neurology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.ORCID 0000-0002-1252-0594
University of Miami · USCentre National de la Recherche Scientifique · FR

Funding

Hypoxic stabilization of OXPHOS complexes in mitochondrial defectsR01GM101225 · NIGMS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI DIAZ, FRANCISCA · 2012 to 2016
$1.3M
NIGMS NIH HHS R01 GM101225
6 · The paper itself

Abstract

Murine fibroblasts deficient in mitochondria respiratory complexes III (CIII) and IV (CIV) produced by either the ablation of

Indexed as

Alkyl and Aryl TransferasesAnimalsCell HypoxiaCell LineCytochrome-c Oxidase DeficiencyDoxycyclineElectron Transport Complex IElectron Transport Complex IIIElectron Transport Complex IVFibroblastsGene Knockout TechniquesGene SilencingHumansHypoxia-Inducible Factor 1, alpha SubunitMembrane ProteinsMiceAlkyl and Aryl TransferasesCOX10 protein, humanDoxycyclineElectron Transport Complex IElectron Transport Complex IIIElectron Transport Complex IVHypoxia-Inducible Factor 1, alpha SubunitMembrane ProteinsReactive Oxygen SpeciesRieske iron-sulfur proteinRNA, Small Interferingcomplex Icomplex IIIcomplex IVCOX10HIF-1αhypoxiamitochondrial respiratory supercomplexesoxidative phosphorylationRieske iron sulfur protein

Identifiers

PMID33003371
PMCPMC7599499
OpenAlexW3089391086

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.