Evidence map›Paper›PMID 33003368›Full record

ArticleInternational journal of molecular sciences2020

An Analysis of Clinical, Surgical, Pathological and Molecular Characteristics of Endometrial Cancer According to Mismatch Repair Status. A Multidisciplinary Approach.

Giulia Dondi, Sara Coluccelli, Antonio De Leo, Simona Ferrari, Elisa Gruppioni, Alessandro Bovicelli, Lea Godino, Camelia Alexandra Coadă, Alessio Giuseppe Morganti, Antonio Giordano and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
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  11. Relevance ofDiagnostics (Basel, Switzerland) · 2022
    Article
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  20. Cancers · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Giulia DondiGynecologic Oncology Unit, Azienda Ospedaliero-Universitaria Policlinico di Sant'Orsola, 40138 Bologna, Italy.
Sara ColuccelliGynecologic Oncology Unit, Azienda Ospedaliero-Universitaria Policlinico di Sant'Orsola, 40138 Bologna, Italy.
Antonio De LeoCentro di Studio e Ricerca delle Neoplasie Ginecologiche (CSR), University of Bologna, 40138 Bologna, Italy.ORCID 0000-0002-3761-5135
Simona FerrariUnit of Medical Genetics, Azienda Ospedaliero-Universitaria Policlinico di Sant'Orsola, University of Bologna, 40138 Bologna, Italy.
Elisa GruppioniLaboratory of Oncologic and Transplantation Molecular Pathology, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, 40138 Bologna, Italy.
Alessandro BovicelliGynecologic Oncology Unit, Azienda Ospedaliero-Universitaria Policlinico di Sant'Orsola, 40138 Bologna, Italy.
Lea GodinoUnit of Medical Genetics, Azienda Ospedaliero-Universitaria Policlinico di Sant'Orsola, University of Bologna, 40138 Bologna, Italy.ORCID 0000-0002-3763-9372
Camelia Alexandra CoadăCenter for Applied Biomedical Research, Alma Mater Studiorum-University of Bologna, 40138 Bologna, Italy.
Alessio Giuseppe MorgantiCentro di Studio e Ricerca delle Neoplasie Ginecologiche (CSR), University of Bologna, 40138 Bologna, Italy.ORCID 0000-0001-9793-3410
Antonio GiordanoSbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia, PA 19122, USA.ORCID 0000-0002-5959-016X
Donatella SantiniCentro di Studio e Ricerca delle Neoplasie Ginecologiche (CSR), University of Bologna, 40138 Bologna, Italy.
Claudio CeccarelliCentro di Studio e Ricerca delle Neoplasie Ginecologiche (CSR), University of Bologna, 40138 Bologna, Italy.ORCID 0000-0003-0743-2087
Daniela TurchettiCentro di Studio e Ricerca delle Neoplasie Ginecologiche (CSR), University of Bologna, 40138 Bologna, Italy.
Pierandrea De IacoGynecologic Oncology Unit, Azienda Ospedaliero-Universitaria Policlinico di Sant'Orsola, 40138 Bologna, Italy.
Anna Myriam PerroneGynecologic Oncology Unit, Azienda Ospedaliero-Universitaria Policlinico di Sant'Orsola, 40138 Bologna, Italy.ORCID 0000-0003-3140-4772
IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola · ITAzienda USL di Bologna · ITUniversity of Bologna · ITUniversity of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since 2016, our hospital has applied tumor testing with immunohistochemistry (IHC) in endometrial cancer in order to detect mutations of mismatch repair genes (MMR). All cases with MMR deficiency proteins expression are sent for genetic testing, except those with

Indexed as

AdultBiomarkers, TumorColorectal Neoplasms, Hereditary NonpolyposisDNA-Binding ProteinsDNA MethylationDNA Mismatch RepairEarly Detection of CancerEndometrial NeoplasmsFemaleGenetic Predisposition to DiseaseGerm-Line MutationHumansMicrosatellite InstabilityMiddle AgedMutL Protein Homolog 1Promoter Regions, GeneticBiomarkers, TumorDNA-Binding ProteinsMLH1 protein, humanMutL Protein Homolog 1endometrial cancerLynch-like cancersLynch syndromeLynch syndrome associated tumorsmicrosatellite instabilitymismatch repair genes

Identifiers

PMID33003368
PMCPMC7582893
OpenAlexW3090988958

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.