Evidence map›Paper›PMID 33003326›Full record

ArticleGenes2020

Differential Regulation of Telomeric Complex by

Anna Deregowska, Monika Pepek, Katarzyna Pruszczyk, Marcin M Machnicki, Maciej Wnuk, Tomasz Stoklosa

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Genetic Biomarkers in Chronic Myeloid Leukemia: What Have We Learned So Far?International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Anna DeregowskaDepartment of Biotechnology, University of Rzeszow, Pigonia 1, 35-310 Rzeszów, Poland.
Monika PepekPostgraduate School of Molecular Medicine, Medical University of Warsaw, Trojdena 2a, 02-091 Warsaw, Poland.
Katarzyna PruszczykDepartment of Immunology, Medical University of Warsaw, Nielubowicza 5, 02-097 Warsaw, Poland.
Marcin M MachnickiPostgraduate School of Molecular Medicine, Medical University of Warsaw, Trojdena 2a, 02-091 Warsaw, Poland.ORCID 0000-0001-8525-543X
Maciej WnukDepartment of Biotechnology, University of Rzeszow, Pigonia 1, 35-310 Rzeszów, Poland.ORCID 0000-0002-8518-6670
Tomasz StoklosaDepartment of Tumor Biology and Genetics, Medical University of Warsaw, Pawinskiego 7, 02-106 Warsaw, Poland.ORCID 0000-0001-6918-5056
Medical University of Warsaw · PLUniversity of Rzeszów · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Telomeres are specialized nucleoprotein complexes, localized at the physical ends of chromosomes, that contribute to the maintenance of genome stability. One of the features of chronic myeloid leukemia (CML) cells is a reduction in telomere length which may result in increased genomic instability and progression of the disease. Aberrant telomere maintenance in CML is not fully understood and other mechanisms such as the alternative lengthening of telomeres (ALT) are involved. In this work, we employed five

Indexed as

Gene Expression Regulation, LeukemicTelomereFusion Proteins, bcr-ablHigh-Throughput Nucleotide SequencingHumansLeukemia, Myelogenous, Chronic, BCR-ABL PositiveSignal TransductionSingle-Cell AnalysisTumor Cells, CulturedBCR-ABL1 fusion protein, humanFusion Proteins, bcr-ablalternative lengthening of telomeresBCR-ABL1blast crisischronic myeloid leukemianext-generation sequencingshelterin complextelomerasetelomere length

Identifiers

PMID33003326
PMCPMC7601685
OpenAlexW3089487255

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.