Evidence map›Paper›PMID 33003051›Full record

ArticleMedical care2020

Facility Variation in Troponin Ordering Within the Veterans Health Administration.

Philip W Chui, Denise Esserman, Lori A Bastian, Jeptha P Curtis, Parul U Gandhi, Lindsey Rosman, Nihar Desai, Ronald G Hauser

Open access · greenAbstract read
In one paragraph

Article in Medical care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Philip W ChuiSection of Cardiovascular Medicine, Department of Internal Medicine.
Denise EssermanSchool of Public Health, Yale University School of Medicine, New Haven, CT.
Lori A BastianPain Research, Informatics, Multimorbidities, and Education (PRIME) Center, VA Connecticut Healthcare System, West Haven.
Jeptha P CurtisSection of Cardiovascular Medicine, Department of Internal Medicine.
Parul U GandhiSection of Cardiovascular Medicine, Department of Internal Medicine.
Lindsey RosmanDepartment of Medicine, Division of Cardiology, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Nihar DesaiSection of Cardiovascular Medicine, Department of Internal Medicine.
Ronald G HauserPain Research, Informatics, Multimorbidities, and Education (PRIME) Center, VA Connecticut Healthcare System, West Haven.
Cardiovascular Research Center · BRVA Connecticut Healthcare System · USUniversity of North Carolina at Chapel Hill · USYale New Haven Hospital · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Center for Cardiovascular Outcomes Research at Yale UniversityU01HL105270 · NHLBI · YALE UNIVERSITY · PI CURTIS, JEPTHA PELHAM, KRUMHOLZ, HARLAN MARC · 2010 to 2013
$5.8M
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS U01 HL105270
6 · The paper itself

Abstract

backgroundCurrent United States guidelines recommend troponin as the preferred biomarker in assessing for acute coronary syndrome, but recommendations are limited about which patients to test. Variations in troponin ordering may influence downstream health care utilization.

methodsWe performed a cross-sectional analysis of 3,308,131 emergency department (ED) visits in all 121 acute care facilities within the Veterans Health Administration from 2015 to 2017. We quantified the degree to which case mix and facility characteristics accounted for variations in facility rates in troponin ordering. We then assessed the association between facility quartiles of risk-adjusted troponin ordering and downstream resource utilization [inpatient admissions, noninvasive testing (stress tests, echocardiograms), and invasive procedures (coronary angiograms, percutaneous coronary interventions, and coronary artery bypass grafting surgeries)].

resultsThe proportion of ED visits with troponin orders ranged from 2.2% to 64.5%, with a median of 37.1%. Case mix accounted for 9.5% of the variation in troponin orders; case mix and differences in facility characteristics accounted for 34.6%. Facilities in the highest quartile of troponin ordering, as compared with those in the lowest quartile, had significantly higher rates of inpatient admissions, stress tests, echocardiograms, coronary angiograms, and percutaneous coronary intervention.

conclusionsSignificant variation in troponin utilization exists across Veterans Health Administration facilities and that variation is not well explained by case mix alone. Facilities with higher rates of troponin ordering were associated with more downstream resource utilization.

Indexed as

Acute Coronary SyndromeAgedAged, 80 and overAge FactorsComorbidityCross-Sectional StudiesDiagnosis-Related GroupsEmergency Service, HospitalGuideline AdherenceHumansMiddle AgedPractice Guidelines as TopicPractice Patterns, Physicians'Socioeconomic FactorsTroponinUnited StatesTroponin

Identifiers

PMID33003051
PMCPMC7666100
OpenAlexW3090557282

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.