Evidence map›Paper›PMID 33002860›Full record

Trial reportNeuroImage. Clinical2020

Ultra-high-field sodium MRI as biomarker for tumor extent, grade and IDH mutation status in glioma patients.

Sebastian Regnery, Nicolas G R Behl, Tanja Platt, Nina Weinfurtner, Paul Windisch, Katerina Deike-Hofmann, Felix Sahm, Martin Bendszus, Jürgen Debus, Mark E Ladd and 4 more

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in NeuroImage. Clinical, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Sodium MRI in Pediatric Brain Tumors.AJNR. American journal of neuroradiology · 2025
    Review
  7. Article
  8. Exploring theFrontiers in neuroscience · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. A uniformity correction method to reduce scan time for 7T sodium imaging of brain tumors.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2022
    Article
  13. Simultaneous 3D acquisition ofMagnetic resonance in medicine · 2022
    Article
  14. Article
  15. Review
  16. Review
  17. Sodium MR Neuroimaging.AJNR. American journal of neuroradiology · 2021
    Review
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Sebastian RegneryDepartment of Radiation Oncology, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Clinical Cooperation Unit Radiation Oncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Nicolas G R BehlSiemens Healthcare GmbH, Erlangen, Germany; Division of Medical Physics in Radiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Tanja PlattDivision of Medical Physics in Radiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Nina WeinfurtnerDivision of Radiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Paul WindischDepartment of Radiation Oncology, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany.
Katerina Deike-HofmannDivision of Radiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Felix SahmDepartment of Neuropathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, 69120 Heidelberg, Germany; CCU Neuropathology, German Consortium for Translational Cancer Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Martin BendszusDepartment of Neuroradiology, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany.
Jürgen DebusDepartment of Radiation Oncology, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Clinical Cooperation Unit Radiation Oncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Mark E LaddDivision of Medical Physics in Radiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany; Faculty of Physics and Astronomy and Faculty of Medicine, University of Heidelberg, Heidelberg, Germany.
Heinz-Peter SchlemmerDivision of Radiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Stefan RiekenDepartment of Radiation Oncology, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Clinical Cooperation Unit Radiation Oncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Sebastian AdebergDepartment of Radiation Oncology, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Clinical Cooperation Unit Radiation Oncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Daniel PaechDivision of Radiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany. Electronic address: d.paech@dkfz.de.
German Cancer Research Center · DEUniversity Hospital Heidelberg · DEHeidelberg University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis prospective clinical trial investigated sodium (

methods28 glioma patients underwent

resultsThe

conclusions

Indexed as

Brain NeoplasmsGliomaBiomarkersDNA MethylationDNA Modification MethylasesDNA Repair EnzymesHumansIsocitrate DehydrogenaseMagnetic Resonance ImagingMutationSodiumTumor Suppressor ProteinsBiomarkersDNA Modification MethylasesDNA Repair EnzymesIsocitrate DehydrogenaseSodiumTumor Suppressor ProteinsGlioblastomaGliomaIDH mutationNon-invasive biomarkerSodium imagingUltra-high-field MRI

Identifiers

PMID33002860
PMCPMC7527584
OpenAlexW3085471507

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.