Evidence map›Paper›PMID 33002635›Full record

ArticleJournal of clinical epidemiology2021

PCORnet® 2020: current state, accomplishments, and future directions.

Christopher B Forrest, Kathleen M McTigue, Adrian F Hernandez, Lauren W Cohen, Henry Cruz, Kevin Haynes, Rainu Kaushal, Abel N Kho, Keith A Marsolo, Vinit P Nair and 7 more

Abstract read
In one paragraph

Article in Journal of clinical epidemiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 133 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
133citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

133 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. Trial
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. AI-enabled Living Labs: Accelerating innovation in multiple sclerosis care and research.Multiple sclerosis (Houndmills, Basingstoke, England) · 2026
    Review
  17. Article
  18. Analysis of a PCORnetCommunications medicine · 2026
    Article
  19. Observational
  20. Article

73 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Christopher B ForrestApplied Clinical Research Center, Children's Hospital of Philadelphia, 2716 South St., Suite 11-473, Philadelphia, PA 19146, USA. Electronic address: forrestc@email.chop.edu.
Kathleen M McTigueDepartment of Medicine, University of Pittsburgh, 230 McKee Place, Suite 600, Pittsburgh, PA 15213 USA.
Adrian F HernandezDuke Clinical Research Institute, Duke University School of Medicine, 200 Trent Drive, Durham, NC 27710, USA.
Lauren W CohenDuke Clinical Research Institute, Duke University School of Medicine, 200 Trent Drive, Durham, NC 27710, USA.
Henry CruzWeill Cornell Medicine and New York-Presbyterian Hospital, 515 E 71st St, New York, NY 10021, USA.
Kevin HaynesScientific Affairs, HealthCore Inc., 123 Justison St, Wilmington, DE 19801, USA.
Rainu KaushalWeill Cornell Medicine and New York-Presbyterian Hospital, 515 E 71st St, New York, NY 10021, USA.
Abel N KhoCenter for Health Information Partnerships, Feinberg School of Medicine, 625 N. Michigan Ave, Chicago, IL 60611, USA.
Keith A MarsoloDuke Clinical Research Institute, Duke University School of Medicine, 200 Trent Drive, Durham, NC 27710, USA.
Vinit P NairPRACnet, 15 South Main Street, Sharon, MA 02067, USA.
Richard PlattHarvard Medical School Department of Population Medicine, Harvard Pilgrim Health Care Institute, 401 Park Drive, Boston, MA 02215, USA.
Jon E PuroOCHIN, Inc., 1881 SW Naito Pkwy, Portland, OR 97201, USA.
Russell L RothmanInstitute for Medicine and Public Health, Vanderbilt University Medical Center, 1161 21st Ave S, Nashville, TN 37232, USA.
Elizabeth A ShenkmanDepartment of Health Outcomes and Biomedical Informatics, College of Medicine, University of Florida, 1600 SW Archer Rd, Gainesville, FL 32610, USA.
Lemuel Russell WaitmanDepartment of Internal Medicine, Division of Medical Informatics, University of Kansas Medical Center, 3901 Rainbow Blvd, Kansas City, KS 66160, USA.
Neely A WilliamsInstitute for Medicine and Public Health, Vanderbilt University Medical Center, 1161 21st Ave S, Nashville, TN 37232, USA.
Thomas W CartonLouisiana Public Health Institute, 1515 Poydras St, New Orleans, LA 70112, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe PCORnet, a clinical research network developed for patient-centered outcomes research on a national scale. STUDY DESIGN AND

settingDescriptive study of the current state and future directions for PCORnet. We conducted cross-sectional analyses of the health systems and patient populations of the 9 Clinical Research Networks and 2 Health Plan Research Networks that are part of PCORnet.

resultsWithin the Clinical Research Networks, electronic health data are currently collected from 337 hospitals, 169,695 physicians, 3,564 primary care practices, 338 emergency departments, and 1,024 community clinics. Patients can be recruited for prospective studies from any of these clinical sites. The Clinical Research Networks have accumulated data from 80 million patients with at least one visit from 2009 to 2018. The PCORnet Health Plan Research Network population of individuals with a valid enrollment segment from 2009 to 2019 exceeds 60 million individuals, who on average have 2.63 years of follow-up.

conclusionPCORnet's infrastructure comprises clinical data from a diverse cohort of patients and has the capacity to rapidly access these patient populations for pragmatic clinical trials, epidemiological research, and patient-centered research on rare diseases.

Indexed as

Biomedical ResearchPatient SelectionTreatment OutcomeElectronic Health RecordsHumansInformation DisseminationInformation ServicesPragmatic Clinical Trials as TopicProspective StudiesBig dataClinical research networkDistributed data networkElectronic health recordsHealth plan research networkLearning health systemPCORnetPragmatic clinical trials

Identifiers

PMID33002635
PMCPMC7521354

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.