Evidence map›Paper›PMID 33002458›Full record

ReviewProgress in cardiovascular diseases

Implications of obesity across the heart failure continuum.

Andrew Elagizi, Salvatore Carbone, Carl J Lavie, Mandeep R Mehra, Hector O Ventura

Open access · greenAbstract readReview
In one paragraph

Review in Progress in cardiovascular diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. THE OBESITY PARADOX IN HEART FAILURE: TIME TO MOVE FORWARD.Transactions of the American Clinical and Climatological Association · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Body mass index and survival in people with heart failure.Heart (British Cardiac Society) · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Observational
  17. Is There an Obesity Paradox in Cardiogenic Shock?Journal of the American Heart Association · 2022
    Article
  18. Taking the Obesity Paradox to New Heights in Cerebral Atherosclerosis.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Andrew ElagiziDepartment of Cardiovascular Diseases; John Ochsner Heart and Vascular Institute, Ochsner Clinical School-the University of Queensland School of Medicine, New Orleans, LA, United States of America.
Salvatore CarboneDepartment of Kinesiology & Health Sciences, College of Humanities & Sciences, Virginia Commonwealth University, Richmond, VA, United States of America; VCU Pauley Heart Center, Division of Cardiology, Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA, United States of America.
Carl J LavieDepartment of Cardiovascular Diseases; John Ochsner Heart and Vascular Institute, Ochsner Clinical School-the University of Queensland School of Medicine, New Orleans, LA, United States of America. Electronic address: clavie@ochsner.org.
Mandeep R MehraCenter for Advanced Heart Disease, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America.
Hector O VenturaDepartment of Cardiovascular Diseases; John Ochsner Heart and Vascular Institute, Ochsner Clinical School-the University of Queensland School of Medicine, New Orleans, LA, United States of America.
Ochsner Medical Center · USHarvard University · USVirginia Commonwealth University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The obesity paradox, which suggests a survival advantage for the obese in heart failure (HF) has sparked debate in the medical community. Studies demonstrate a survival advantage in obese patients with HF, including those with advanced HF requiring continuous inotropic support for palliation or disease modifying therapy with a left ventricular assist device (LVAD) or heart transplantation (HT). Importantly, the obesity paradox is affected by the level of cardiorespiratory fitness (CRF). It is now recommended that HF patients with body mass index ≥35 kg/m

Indexed as

Cardiorespiratory FitnessVentricular Function, LeftAdiposityBariatric SurgeryBody Mass IndexHeart-Assist DevicesHeart Disease Risk FactorsHeart FailureHeart TransplantationHumansObesityProsthesis ImplantationRecovery of FunctionRisk AssessmentTreatment OutcomeWeight LossCardiorespiratory fitnessCardiovascular diseaseHeart failureHeart transplantLeft ventricular assist deviceObesity

Identifiers

PMID33002458
PMCPMC7521376
OpenAlexW3091500783

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.