ArticleImmunity2020
In Situ Maturation and Tissue Adaptation of Type 2 Innate Lymphoid Cell Progenitors.
Open access · bronzeAbstract read
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Article in Immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers.
0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed
6.9field-weighted citation impact, top 2% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
88 citing papers in PubMed, 139 citations in OpenAlex.
- Group 2 innate lymphoid cells program pulmonary adaptive immunity via granulocyte-macrophage colony-stimulating factor.The Journal of allergy and clinical immunology · 2026Article
- Innate lymphoid cells in rheumatoid arthritis as mediators of pathology and resolution.Nature reviews. Rheumatology · 2026Review
- Single-cell analysis of recruited ILC2 cell fate during transition from circulation to establishment of tissue residency.Journal of immunology (Baltimore, Md. : 1950) · 2026Article
- Type 2 lymphocytes restrict type 3 lymphocytes during liver fibrosis and colocalize in fibroblast niches.Science advances · 2026Article
- The development of innate lymphoid cells.Nature immunology · 2026Review
- Mucosal Remodeling in Chronic Rhinosinusitis with Nasal Polyps: The Role of Innate Lymphoid Cells and Reprogramming Under IL-4Rα Blockade.International journal of molecular sciences · 2026Review
- Early life group 2 innate lymphoid cells in health and disease.Molecular and cellular pediatrics · 2026Review
- The IL-33-ILC2 axis: a key regulator of type 2 immunity in respiratory disease.Frontiers in immunology · 2026Review
- Stem cell factor 248 shapes ILC2 transcriptional programs and promotes mucosal inflammation in allergic asthma.Frontiers in immunology · 2026Article
- Article
- Cellular Cosmetics: How Innate Lymphoid Cells Can Recontour the Tumour Microenvironment.European journal of immunology · 2025Review
- Choroid Plexus Fibroblast-ILC2 Niche Promotes Adult Hippocampal Neurogenesis after Traumatic Brain Injury.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Rapid group-2 innate lymphoid cell mobilization from the intestine aids in early lung defense and repair.Cell reports · 2025Article
- ILC2 Diversity, Location, and Function in Pulmonary Disease.Immunological reviews · 2025Review
- RAG suppresses group 2 innate lymphoid cells.eLife · 2025Article
- Regulation of innate lymphoid cell by microbial metabolites.Journal of molecular medicine (Berlin, Germany) · 2025Review
- Chronic Inflammation in Asthma: Looking Beyond the Th2 Cell.Immunological reviews · 2025Review
- Tissue-resident immune cells: from defining characteristics to roles in diseases.Signal transduction and targeted therapy · 2025Review
- Cell-type specific, inducible and acute degradation of targeted protein in mice by two degron systems.Nature communications · 2024Article
- CTLA-4 expressing innate lymphoid cells modulate mucosal homeostasis in a microbiota dependent manner.Nature communications · 2024Article
28 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
20 authors at 11 institutions in 3 countries.
Patrice ZeisMax Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany; International Max Planck Research School for Molecular and Cellular Biology (IMPRS-MCB), Freiburg, Germany; Faculty of Biology, University of Freiburg, Freiburg, Germany.
Mi LianWürzburg Institute of Systems Immunology, Max Planck Research Group at the Julius-Maximilians-Universität Würzburg, Würzburg, Germany; Faculty of Biology, University of Freiburg, Freiburg, Germany; Institute of Medical Microbiology and Hygiene, University Medical Center Freiburg, Freiburg, Germany.
Xiying FanHoward Hughes Medical Institute, Immunology Program, and Ludwig Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Josip S HermanMax Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany; International Max Planck Research School for Molecular and Cellular Biology (IMPRS-MCB), Freiburg, Germany; Faculty of Biology, University of Freiburg, Freiburg, Germany.
Daniela C HernandezGerman Rheumatism Research Center (DRFZ), Leibniz Association, Berlin, Germany; Medical Department I, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Rebecca GentekAix Marseille Université, CNRS, INSERM, CIML, Marseille, France.
Shlomo EliasHoward Hughes Medical Institute, Immunology Program, and Ludwig Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Cornelia SymowskiDepartment of Infection Biology, University Hospital Erlangen and Friedrich-Alexander University Erlangen-Nuremberg (FAU), Erlangen, Germany.
Konrad KnöpperWürzburg Institute of Systems Immunology, Max Planck Research Group at the Julius-Maximilians-Universität Würzburg, Würzburg, Germany.
Nina PeltokangasMax Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany; Faculty of Biology, University of Freiburg, Freiburg, Germany.
Christin FriedrichWürzburg Institute of Systems Immunology, Max Planck Research Group at the Julius-Maximilians-Universität Würzburg, Würzburg, Germany; Institute of Medical Microbiology and Hygiene, University Medical Center Freiburg, Freiburg, Germany.
Remi Doucet-LadevezeWürzburg Institute of Systems Immunology, Max Planck Research Group at the Julius-Maximilians-Universität Würzburg, Würzburg, Germany.
Agnieszka M KabatMax Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
Richard M LocksleyHoward Hughes Medical Institute and Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.
David VoehringerDepartment of Infection Biology, University Hospital Erlangen and Friedrich-Alexander University Erlangen-Nuremberg (FAU), Erlangen, Germany.
Marc BajenoffAix Marseille Université, CNRS, INSERM, CIML, Marseille, France.
Alexander Y RudenskyHoward Hughes Medical Institute, Immunology Program, and Ludwig Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Chiara RomagnaniGerman Rheumatism Research Center (DRFZ), Leibniz Association, Berlin, Germany; Medical Department I, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Dominic GrünMax Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany; CIBSS-Centre for Integrative Biological Signaling Studies, University of Freiburg, Freiburg, Germany. Electronic address: gruen@ie-freiburg.mpg.de.
Georg GasteigerWürzburg Institute of Systems Immunology, Max Planck Research Group at the Julius-Maximilians-Universität Würzburg, Würzburg, Germany; Institute of Medical Microbiology and Hygiene, University Medical Center Freiburg, Freiburg, Germany. Electronic address: georg.gasteiger@uni-wuerzburg.de.
Howard Hughes Medical Institute · USMax Planck Institute of Immunobiology and Epigenetics · DEInserm · FRUniversity Medical Center Freiburg · DEUniversity of Würzburg · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DEGerman Rheumatism Research Centre · DEInstitute of Medical Microbiology and Hygiene · DELeibniz Association · DEUniversitätsklinikum Erlangen · DEUniversity of Freiburg · DE
Funding
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4MRole of miRNAs in Th2-Driven inflammation in AsthmaP01HL107202 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ANSEL, KARL MARK · 2012 to 2023
$23.3MEuropean Research Council 647257European Research Council 759176European Research Council 818846NCI NIH HHS P30 CA008748NHLBI NIH HHS P01 HL107202
Abstract
Innate lymphoid cells (ILCs) are generated early during ontogeny and persist predominantly as tissue-resident cells. Here, we examined how ILCs are maintained and renewed within tissues. We generated a single cell atlas of lung ILC2s and found that Il18r1
Indexed as
AnimalsCell DifferentiationCells, CulturedFemaleHumansImmunity, InnateInterleukin-18 Receptor alpha SubunitLungLymphocytesLymphoid Progenitor CellsMiceMice, Inbred C57BLPromyelocytic Leukemia Zinc Finger ProteinSignal TransductionSingle-Cell AnalysisT Cell Transcription Factor 1Interleukin-18 Receptor alpha SubunitPromyelocytic Leukemia Zinc Finger ProteinT Cell Transcription Factor 1Transcription Factorsbone marrowILC2ILCPimmune system developmentInnate lymphoid cells (ILC)Nippostrongylus Brasiliensisprogenitorssingle cell atlassingle-cell RNA-seqtissue immunity
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.