Evidence map›Paper›PMID 33002370›Full record

ArticleJournal of speech, language, and hearing research : JSLHR2020

Language Development From Early Childhood to Adolescence in Youths With Fragile X Syndrome.

Nancy C Brady, Kandace Fleming, Shelley L Bredin-Oja, Heather Fielding-Gebhardt, Steven F Warren

Abstract read
In one paragraph

Article in Journal of speech, language, and hearing research : JSLHR, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. The impact of individual factors on linguistic alignment of autistic boys and their mothers.Autism : the international journal of research and practice · 2026
    Article
  3. Article
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  7. Article
  8. Language Skills Influence Transition Planning in Adolescents With Fragile X Syndrome.American journal on intellectual and developmental disabilities · 2024
    Article
  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nancy C BradyDepartment of Speech-Language-Hearing: Sciences & Disorders, The University of Kansas, Lawrence.
Kandace FlemingLife Span Institute, The University of Kansas, Lawrence.
Shelley L Bredin-OjaDepartment of Speech-Language-Hearing: Sciences & Disorders, The University of Kansas, Lawrence.
Heather Fielding-GebhardtLife Span Institute, The University of Kansas, Lawrence.
Steven F WarrenDepartment of Speech-Language-Hearing: Sciences & Disorders, The University of Kansas, Lawrence.

Funding

Using PCORnet to Expand the DS-CONNECT Cohort Through Healthcare System Recruitment, Incorporating Electronic Health Records, and Assessing Self-DeterminationU54HD090216 · NICHD · UNIVERSITY OF KANSAS LAWRENCE · PI COLOMBO, JOHN A. · 2016 to 2020
$6.2M
The Effects of Parenting on the Development and Behavior of Adolescents with FXSR01HD084563 · NICHD · UNIVERSITY OF KANSAS LAWRENCE · PI NANCY CAROLINE BRADY · 2016 to 2026
$4.7M
NICHD NIH HHS R01 HD084563NICHD NIH HHS U54 HD090216
6 · The paper itself

Abstract

Purpose The aim of this study was to investigate language growth in individuals with fragile X syndrome (FXS) from early childhood to adolescence and the influence of maternal responsivity on language growth. Method We conducted a longitudinal analysis of language development in 55 youths (44 males, 11 females) with FXS. Data collection spanned the ages of 11-216 months. We measured expressive and receptive vocabulary with standardized tests. The number of different words and mean length of utterance were obtained from language sample analyses of mother-child interactions. We also measured maternal comments (responsivity indicator) produced during the language samples and child nonverbal IQ. Results Growth models indicated that rates of number of different words and receptive vocabulary were related to maternal commenting. Mean length of utterance did not change significantly over time. Expressive vocabulary measured with a standardized test grew, but the growth was not related to maternal commenting. Nonverbal IQ was related to all language outcomes at age of 10 years and to changes over time in vocabulary. Visual analysis indicated that the highest scores on standardized tests were produced by girls; however, measures derived from language sample analyses appeared similar for boys and girls. Language models for boys only were similar to the total sample models with lower scores at age of 10 years for some outcomes. Conclusion Results of persistent language impairments for most youths with FXS suggest the need for continued, focused interventions aimed at improved language productions in addition to a responsive environment. Supplemental Material https://doi.org/10.23641/asha.13022825.

Indexed as

Fragile X SyndromeAdolescentChildChild, PreschoolFemaleHumansLanguageLanguage DevelopmentLanguage TestsMaleVocabulary

Identifiers

PMID33002370
PMCPMC8582761

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.