ArticleJournal of medical Internet research2020
Epidemiological Parameters of COVID-19: Case Series Study.
Article in Journal of medical Internet research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.
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Who cites it
30 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Smartphone-Based Digital Health Interventions: A Comprehensive Systematic Review of Efficacy for Cardiovascular and Cerebrovascular Outcomes.Journal of medical systems · 2025Pooled it
- Assessing changes in incubation period, serial interval, and generation time of SARS-CoV-2 variants of concern: a systematic review and meta-analysis.BMC medicine · 2023Pooled it
- The Proportion of SARS-CoV-2 Infections That Are Asymptomatic : A Systematic Review.Annals of internal medicine · 2021Pooled it
- Use of the test-negative design to estimate the protective effect of a scalar immune measure: a simulation analysis.American journal of epidemiology · 2026Article
- Estimation of undetected asymptomatic infections of COVID-19: a mathematical modeling approach.Scientific reports · 2025Article
- Optimizing Contact Network Topological Parameters of Urban Populations Using the Genetic Algorithm.Entropy (Basel, Switzerland) · 2024Article
- Mathematical modeling of contact tracing and stability analysis to inform its impact on disease outbreaks; an application to COVID-19.Infectious Disease Modelling · 2024Article
- Modeling the health impact of increasing vaccine coverage and nonpharmaceutical interventions against coronavirus disease 2019 in Ghana.Pathogens and global health · 2024Article
- Evaluation of the EsteR Toolkit for COVID-19 Decision Support: Sensitivity Analysis and Usability Study.JMIR formative research · 2023Article
- Age-Stratified Model to Assess Health Outcomes of COVID-19 Vaccination Strategies, Ghana.Emerging infectious diseases · 2023Article
- Tracing and testing multiple generations of contacts to COVID-19 cases: cost-benefit trade-offs.Royal Society open science · 2022Article
- The impact of three progressively introduced interventions on second wave daily COVID-19 case numbers in Melbourne, Australia.BMC infectious diseases · 2022Article
- A Cross-Sectional Study of Exposure Factors Associated with Seropositivity for SARS-CoV-2 Antibodies during the Second Epidemic Wave among a Sample of the University of Corsica (France).International journal of environmental research and public health · 2022Article
- A quantitative assessment of epidemiological parameters required to investigate COVID-19 burden.Epidemics · 2021Article
- Shrinkage in serial intervals across transmission generations of COVID-19.Journal of theoretical biology · 2021Article
- Assessment of Simulated Surveillance Testing and Quarantine in a SARS-CoV-2-Vaccinated Population of Students on a University Campus.JAMA health forum · 2021Article
- Impact of Mass Workplace COVID-19 Rapid Testing on Health and Healthcare Resource Savings.International journal of environmental research and public health · 2021Article
- A Cost-Benefit Analysis of the COVID-19 Asymptomatic Mass Testing Strategy in the North Metropolitan Area of Barcelona.International journal of environmental research and public health · 2021Article
- In pursuit of the right tail for the COVID-19 incubation period.Public health · 2021Review
- Effect of manual and digital contact tracing on COVID-19 outbreaks: a study on empirical contact data.Journal of the Royal Society, Interface · 2021Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe estimates of several key epidemiological parameters of the COVID-19 pandemic are often based on small sample sizes or are inaccurate for various reasons.
objectiveThe aim of this study is to obtain more robust estimates of the incubation period, serial interval, frequency of presymptomatic transmission, and basic reproduction number (R
methodsWe systematically retrieved and screened 20,658 reports of laboratory-confirmed COVID-19 cases released by the health authorities of China, Japan, and Singapore. In addition, 9942 publications were retrieved from PubMed and China National Knowledge Infrastructure (CNKI) through April 8, 2020. To be eligible, a report had to contain individual data that allowed for accurate estimation of at least one parameter. Widely used models such as gamma distributions were fitted to the data sets and the results with the best-fitting values were presented.
resultsIn total, 1591 cases were included for the final analysis. The mean incubation period (n=687) and mean serial interval (n=1015 pairs) were estimated to be 7.04 (SD 4.27) days and 6.49 (SD 4.90) days, respectively. In 40 cases (5.82%), the incubation period was longer than 14 days. In 32 infector-infectee pairs (3.15%), infectees' symptom onsets occurred before those of infectors. Presymptomatic transmission occurred in 129 of 296 infector-infectee pairs (43.58%). R
conclusionsThis study provides robust estimates of several epidemiological parameters of COVID-19. The findings support the current practice of 14-day quarantine of persons with potential exposure, but also suggest the need for additional measures. Presymptomatic transmission together with the asymptomatic transmission reported by previous studies highlight the importance of adequate testing, strict quarantine, and social distancing.
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