Evidence map›Paper›PMID 33001561›Full record

ArticleAutism research : official journal of the International Society for Autism Research2020

The Autism Impact Measure (AIM): Examination of Sensitivity to Change.

Micah O Mazurek, Coleen Carlson, Mary Baker-Ericzén, Eric Butter, Megan Norris, Christopher Barr, Stephen Kanne

2 registry-linked trialsOpen access · greenAbstract read
In one paragraph

Article in Autism research : official journal of the International Society for Autism Research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06908187 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Parent Training for Autistic Toddlers: Development and Preliminary Testing

TypeinterventionalSponsorOregon Health and Science UniversityRan2025 to 2028Enrolled120ConditionsAutism Spectrum DisorderArmsOpt-In Early Latinx intervention, Opt-In Early Rural Intervention
NCT07259044 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Global Strategies, Local Impact: Testing Scalable Caregiver Interventions for Autism in Low-Resource Health Systems

TypeinterventionalSponsorIndiana UniversityRan2026 to 2030Enrolled320ConditionsAutism Spectrum Disorder, Autism, ASDArmsProfessionally-facilitated groups, Peer-facilitated groups
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
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  4. Short Report: An Examination of Children's Autism Traits and Their Association With Family Experience.Autism research : official journal of the International Society for Autism Research · 2026
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  16. Measurement invariance of the Autism Impact Measure (AIM) across sex in children with autism spectrum disorder.Autism research : official journal of the International Society for Autism Research · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Micah O MazurekDepartment of Human Services, School of Education and Human Development, University of Virginia, Charlottesville, Virginia, USA.ORCID 0000-0001-7715-6538
Coleen CarlsonDepartment of Psychology, Texas Institute for Measurement, Evaluation, and Statistics, University of Houston, Houston, Texas, USA.
Mary Baker-EriczénChild and Adolescent Services Research Center, Autism Discovery Institute, Rady Children's Hospital, San Diego, California, USA.
Eric ButterDepartment of Pediatrics and Psychology, The Ohio State University, Nationwide Children's Hospital, Columbus, Ohio, USA.
Megan NorrisChild Development Center, Nationwide Children's Hospital, Columbus, Ohio, USA.
Christopher BarrTexas Institute for Measurement, Evaluation, and Statistics, University of Houston, Houston, Texas, USA.
Stephen KanneDepartment of Psychiatry, Weill Cornell Medical College, New York, USA.
Nationwide Children's Hospital · USUniversity of Houston · USAutism Research Institute · USCornell University · USUniversity of Virginia · US

Funding

The Autism Impact Measure: A New Tool for Treatment Outcome MeasurementR01MH097726 · NIMH · UNIVERSITY OF MISSOURI-COLUMBIA · PI KANNE, STEPHEN M · 2013 to 2015
$3.9M
NIMH NIH HHS R01 MH097726
6 · The paper itself

Abstract

The Autism Impact Measure (AIM) was designed specifically for treatment-outcome assessment in children with ASD, focusing on treatment-relevant aspects of symptom presentation and efficient detection of short-term improvement. The AIM demonstrated strong reliability and validity in initial psychometric studies. The current study evaluated the AIM's sensitivity to change across well-established treatments. The sample included 471 children with ASD (ages 2-14) participating in one of six treatments. The AIM was administered at baseline and 6-week intervals and a battery of domain-specific concurrent measures was also administered. A longitudinal repeated measures design examined the degree to which: (a) AIM domain scores changed over time in response to treatment and (b) change in AIM domains was associated with change in measures of similar constructs. Results across growth curve models indicated that AIM domains are sensitive to change in symptoms across treatment. Across all models, symptoms decreased over time, with some deceleration in rate of improvement. For all AIM domains except Repetitive Behavior, symptoms improved as a function of treatment group. Correlations of change between AIM and other measures varied across domains (from 0.01-0.43 across measures). This was the first large-scale study to systematically evaluate sensitivity to change in a measure of core ASD symptoms. The results provide support for the AIM's ability to detect short-term improvement across symptom domains and indicate that AIM domains are sensitive to change overall and as a function of different treatment conditions. The brief repeated assessment window also highlights the AIM's utility for detecting improvements across short-term treatments. Autism Res 2020, 13: 1867-1879. © 2020 International Society for Autism Research and Wiley Periodicals LLC LAY SUMMARY: Good measures are important for assessing outcomes in children with autism. However, there are few tools for tracking short-term changes in autism symptoms. This study tested a new measure, the Autism Impact Measure (AIM), in a large group of children with autism. The results showed that the AIM appears to be a valid and accurate tool for measuring autism symptoms. The AIM may be a helpful tool for researchers and clinicians interested in tracking short-term improvements in autism symptoms.

Indexed as

Autistic DisorderAdolescentChildChild, PreschoolCognitionHumansPsychometricsReproducibility of Resultsassessmentautism spectrum disorderautism symptomsmeasurementtreatment outcome

Identifiers

PMID33001561
PMCPMC7722077
OpenAlexW3090599559

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.