Evidence map›Paper›PMID 33001410›Full record

ReviewGeroScience2020

Sarcopenia during COVID-19 lockdown restrictions: long-term health effects of short-term muscle loss.

Richard Kirwan, Deaglan McCullough, Tom Butler, Fatima Perez de Heredia, Ian G Davies, Claire Stewart

Registry-linked trialOpen access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in GeroScience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05449379 (Evaluation of Influence of Proprietary Physical Training Program on Quality of Life, Physical Endurance, Function of Muscles and Myokines Profile in Patients After COVID-19 Infection.), which is not on this map. Cited by 168 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
168citing papers in PubMed, 10 pooled it
32.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05449379 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Evaluation of Influence of Proprietary Physical Training Program on Quality of Life, Physical Endurance, Function of Muscles and Myokines Profile in Patients After COVID-19 Infection.

TypeinterventionalSponsorMedical University of BialystokRan2022 to 2025Enrolled60ConditionsCOVID-19, RehabilitationArmsRespiratory training with the use of resistance set on respiratory muscle trainer, Respiratory training without resistance set on respiratory muscle trainer
3 · Its place in the literature

Who cites it

168 citing papers in PubMed, 10 syntheses or guidelines pooled it, 334 citations in OpenAlex.

  1. Pooled it
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  9. Obesity and COVID-19. A necessary position statement.Endocrinologia, diabetes y nutricion · 2021
    Guideline
  10. Obesity and COVID-19. A necessary position statement.Endocrinologia, diabetes y nutricion · 2021
    Guideline
  11. Trial
  12. Trial
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  16. Observational
  17. Review
  18. Tracking Sarcopenia and Physical Activities Among Korean Adults Aged 50 Years and Older During COVID-19 Pandemic.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026
    Article
  19. Article
  20. Article

108 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Richard KirwanSchool of Biological and Environmental Sciences, Liverpool John Moores University, Liverpool, UK. r.p.kirwan@2018.ljmu.ac.uk.ORCID 0000-0003-4645-0077
Deaglan McCulloughResearch Institute of Sport and Exercise Science, Liverpool John Moores University, Liverpool, UK.ORCID 0000-0002-9882-9639
Tom ButlerDepartment of Clinical Sciences and Nutrition, University of Chester, Chester, UK. t.butler@chester.ac.uk.ORCID 0000-0003-0818-1566
Fatima Perez de HerediaSchool of Biological and Environmental Sciences, Liverpool John Moores University, Liverpool, UK.ORCID 0000-0002-2537-3327
Ian G DaviesResearch Institute of Sport and Exercise Science, Liverpool John Moores University, Liverpool, UK.ORCID 0000-0003-3722-8466
Claire StewartResearch Institute of Sport and Exercise Science, Liverpool John Moores University, Liverpool, UK.ORCID 0000-0002-8104-4819
Liverpool John Moores University · GBUniversity of Chester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic is an extraordinary global emergency that has led to the implementation of unprecedented measures in order to stem the spread of the infection. Internationally, governments are enforcing measures such as travel bans, quarantine, isolation, and social distancing leading to an extended period of time at home. This has resulted in reductions in physical activity and changes in dietary intakes that have the potential to accelerate sarcopenia, a deterioration of muscle mass and function (more likely in older populations), as well as increases in body fat. These changes in body composition are associated with a number of chronic, lifestyle diseases including cardiovascular disease (CVD), diabetes, osteoporosis, frailty, cognitive decline, and depression. Furthermore, CVD, diabetes, and elevated body fat are associated with greater risk of COVID-19 infection and more severe symptomology, underscoring the importance of avoiding the development of such morbidities. Here we review mechanisms of sarcopenia and their relation to the current data on the effects of COVID-19 confinement on physical activity, dietary habits, sleep, and stress as well as extended bed rest due to COVID-19 hospitalization. The potential of these factors to lead to an increased likelihood of muscle loss and chronic disease will be discussed. By offering a number of home-based strategies including resistance exercise, higher protein intakes and supplementation, we can potentially guide public health authorities to avoid a lifestyle disease and rehabilitation crisis post-COVID-19. Such strategies may also serve as useful preventative measures for reducing the likelihood of sarcopenia in general and in the event of future periods of isolation.

Indexed as

COVID-19Feeding BehaviorHumansLife StylePandemicsQuality of LifeRisk FactorsSarcopeniaSARS-CoV-2Sedentary BehaviorAppetite regulationCOVID-19InflammationObesityPhysical activitySarcopenia

Identifiers

PMID33001410
PMCPMC7528158
OpenAlexW3090079039

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.