Evidence map›Paper›PMID 33001403›Full record

ArticleAging clinical and experimental research2021

Multidimensional Prognostic Index (MPI) in elderly patients with acute myocardial infarction.

Valeria Cammalleri, Michela Bonanni, Francesca Maria Bueti, Andrea Matteucci, Lisa Cammalleri, Giuseppe Stifano, Saverio Muscoli, Francesco Romeo

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In one paragraph

Article in Aging clinical and experimental research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Valeria CammalleriDepartment of Cardiovascular Disease, Tor Vergata University, Via Montpellier 1, 00133, Rome, Italy. v.cammalleri@hotmail.it.ORCID http://orcid.org/0000-0001-5374-8125
Michela BonanniDepartment of Cardiovascular Disease, Tor Vergata University, Via Montpellier 1, 00133, Rome, Italy.
Francesca Maria BuetiDepartment of Cardiovascular Disease, Tor Vergata University, Via Montpellier 1, 00133, Rome, Italy.
Andrea MatteucciDepartment of Cardiovascular Disease, Tor Vergata University, Via Montpellier 1, 00133, Rome, Italy.
Lisa CammalleriDepartment of OrthoGeriatrics, Rehabilitation and Stabilization, Galliera Hospital, Genova, Italy.
Giuseppe StifanoDepartment of Cardiovascular Disease, Tor Vergata University, Via Montpellier 1, 00133, Rome, Italy.
Saverio MuscoliDepartment of Cardiovascular Disease, Tor Vergata University, Via Montpellier 1, 00133, Rome, Italy.
Francesco RomeoDepartment of Cardiovascular Disease, Tor Vergata University, Via Montpellier 1, 00133, Rome, Italy.
University of Rome Tor Vergata · ITEnte Ospedaliero Ospedali Galliera · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundManagement of elderly patients with acute myocardial infarction (AMI) is challenging due to lack of knowledge about the link between fragility, outcomes and interventional procedures.

aimsThe aim of this study was to establish the prognostic role of the Multidimensional Prognostic Index (MPI) in elderly with AMI.

methodsA total of 241 patients ≥ 65 years old with AMI were continuously enrolled in this prospective study and divided into three groups according to the MPI score. The primary endpoint was 30-day mortality. Secondary endpoints were 6-month mortality and rate of adverse events.

resultsIn-hospital overall mortality rate was higher in MPI-3 (p = 0.009). Patients of MPI-3 had a significantly higher mortality rate regarding the primary endpoint with 30-day survival of 78.9%, compared to 97.4% and 97.2%, in MPI-1, MPI-2 (p < 0.001), respectively. The survival rate progressively decreased in the three MPI classes of risk with a 6-month survival of 96.5%, 96.3%, 73.7% in groups MPI-1, MPI-2, and MPI-3 (p < 0.001). Longer length of in-hospital stay was observed in MPI-3 group. In-hospital complications were more frequent in higher MPI score. DISCUSSION: Our findings are in agreement with the results of other studies that evaluated the risk of in-hospital complications and mortality in older patients. In our "real-world" population of elderly hospitalized for AMI we observed poorer outcomes in patients belonged to higher MPI groups.

conclusionsIn the setting of AMI, MPI may be very useful in the daily clinical practice to manage older patients and predict the risk of in-hospital and follow-up complications.

Indexed as

Geriatric AssessmentMyocardial InfarctionAgedHumansLength of StayPrognosisProspective StudiesRisk FactorsAcute coronary syndromeAcute myocardial infarctionFrailtyGeriatric assessment

Identifiers

PMID33001403
PMCPMC8249274
OpenAlexW3091015581

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.