ArticleJapanese journal of radiology2021
Maximum slope of ultrafast dynamic contrast-enhanced MRI of the breast: Comparisons with prognostic factors of breast cancer.
Article in Japanese journal of radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- The diagnostic performance of ultrafast MRI to differentiate benign from malignant breast lesions: a systematic review and meta-analysis.European radiology · 2024Pooled it
- Background parenchymal enhancement in ultrafast MRI: Inter-reader agreement before and after training, and correlations with prognostic factors of breast cancer.European journal of radiology open · 2026Article
- Diagnostic performance of kinetic parameters of ultrafast breast MRI and their associations with immunohistopathological findings of breast carcinoma.Scientific reports · 2026Article
- The role of magnetic resonance imaging (MRI) in breast cancer molecular subtypes.Polish journal of radiology · 2026Review
- Role of Ultrafast Dynamic Contrast-Enhanced MRI in Breast Cancer Prognostication: Correlation Between Early Kinetic Parameters and Tumor Aggressiveness and Histopathologic Characteristics.Journal of the Korean Society of Radiology · 2025Article
- A simplified method for generating maximum slope maps in ultrafast dynamic contrast-enhanced breast magnetic resonance imaging.Radiological physics and technology · 2025Article
- Predictive Performance of Radiomic Features Extracted from Breast MR Imaging in Postoperative Upgrading of Ductal Carcinoma in Situ to Invasive Carcinoma.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025Article
- Abbreviated and Ultrafast Dynamic Contrast-enhanced (DCE) MR Imaging.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025Review
- Superior performance in classification of breast cancer molecular subtype and histological factors by radiomics based on ultrafast MRI over standard MRI: evidence from a prospective study.La Radiologia medica · 2025Observational
- Relationship between kinetic parameters of ultrafast dynamic contrast-enhanced (DCE) MRI and tumor-infiltrating lymphocytes (TILs) in breast cancer.Japanese journal of radiology · 2025Article
- Morphological Assessment of Breast Lesions With Type 2 Dynamic Curves Using DWI and T2WI Based on Breast Imaging Reporting and Data System Lexicon Descriptors.The breast journal · 2025Article
- Analysis of the diagnostic efficacy of ultrasound, MRI, and combined examination in benign and malignant breast tumors.Frontiers in oncology · 2025Article
- Comparison of state-of-the-art biopsy systems for ultrasound-guided breast biopsy using a chicken breast phantom.Journal of medical ultrasonics (2001) · 2024Article
- Clinical role of abbreviated and ultrafast MRI in breast imaging.The British journal of radiology · 2024Review
- Ultrafast MR imaging findings of 2 different subtypes in a male patient with bilateral breast cancer.Radiology case reports · 2024Article
- Clinical Utility of Breast Ultrasound Images Synthesized by a Generative Adversarial Network.Medicina (Kaunas, Lithuania) · 2023Article
- A multiparametric approach to predict triple-negative breast cancer including parameters derived from ultrafast dynamic contrast-enhanced MRI.European radiology · 2023Article
- Correlation of Perfusion Metrics with Ki-67 Proliferation Index and Axillary Involvement as a Prognostic Marker in Breast Carcinoma Cases: A Dynamic Contrast-Enhanced Perfusion MRI Study.Diagnostics (Basel, Switzerland) · 2023Article
- Current State of Artificial Intelligence in Clinical Applications for Head and Neck MR Imaging.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2023Review
- Comparison of Ultrafast Dynamic Contrast-Enhanced (DCE) MRI with Conventional DCE MRI in the Morphological Assessment of Malignant Breast Lesions.Diagnostics (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo determine the relationship between the maximum slope (MS) of ultrafast dynamic contrast-enhanced (DCE)-MRI and prognostic factors of breast cancer.
methodsOne hundred thirteen patients with 118 breast cancers were included in this study. The ultrafast DCE sequence was acquired using a higher parallel imaging factor. Its spatial resolution was 0.9 × 0.9 × 2.5 mm and its temporal resolution was 8.3 s/phase. Each lesion was automatically segmented, and the ROI of highest enhancement in the lesion was identified. In this ROI, the MS was calculated. The MS of each lesion was compared with various prognostic factors of breast cancer.
resultsThe MS of invasive cancer (median: 9.81%/sec) was significantly higher than that of ductal carcinoma in situ (median: 7.26%/sec) (p = 0.001). In the ROC analysis, the area under the ROC curve (AUC) was 0.7295. The MS of invasive cancer with axillary lymph node (LN) metastasis (median: 11.97%/sec) was significantly higher than that without axillary LN metastasis (median: 9.425%/sec) (p = 0.0024). In the ROC analysis, the AUC was 0.7177. In addition, the MS became significantly higher as the level of the proliferation marker ki-67 increased (correlation coefficient: 0.3317) (p = 0.0009).
conclusionsMS of ultrafast DCE-MRI is useful for predicting the prognostic factors of breast cancer. Higher maximum slope (MS) is significantly associated with an invasive breast cancer component. Higher MS is significantly associated with an axillary lymph node metastasis. MS becomes significantly higher with increasing ki-67 (a proliferation marker). Ultrafast MRI is useful for predicting the prognostic factors of breast cancer.
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