Evidence map›Paper›PMID 33001290›Full record

ArticleAnnals of biomedical engineering2021

Sensor Anchoring Improves the Correlation Between Intramuscular Pressure and Muscle Tension in a Rabbit Model.

Shawn M O'Connor, Kenton R Kaufman, Samuel R Ward, Richard L Lieber

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of biomedical engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Shawn M O'ConnorSchool of Exercise and Nutritional Sciences, San Diego State University, San Diego, CA, USA.
Kenton R KaufmanDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.
Samuel R WardDepartment of Orthopaedic Surgery, University of California San Diego, La Jolla, CA, USA.
Richard L LieberDepartment of Orthopaedic Surgery, University of California San Diego, La Jolla, CA, USA. rlieber@sralab.org.ORCID http://orcid.org/0000-0002-7203-4520
Mayo Clinic in Arizona · USSan Diego State University · USShirley Ryan AbilityLab · USUniversity of California San Diego · US

Funding

National Center for Muscle Rehabilitation ResearchR24HD050837 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LIEBER, RICHARD L., WARD, SAMUEL RICHARD · 2005 to 2014
$7.2M
MICROSENSOR FOR INTRAMUSCULAR PRESSURE MEASUREMENTR01HD031476 · NICHD · MAYO CLINIC ROCHESTER · PI KAUFMAN, KENTON R. · 1994 to 2014
$5.3M
San Diego Skeletal Muscle Research CenterP30AR061303 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHEN, JU · 2011 to 2015
$3.3M
Muscle Triglyceride Metabolism Core CenterP30AR058878 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LIEBER, RICHARD L. · 2009 to 2010
$925k
Intraoperative Optimization and Validation of Musculoskeletal ReconstructionI01RX002462 · VA · EDWARD HINES JR VA HOSPITAL · PI LIEBER, RICHARD L. · 2018 to 2025
–
RR&D Senior Research Career Scientist Award ApplicationIK6RX003351 · VA · EDWARD HINES JR VA HOSPITAL · PI LIEBER, RICHARD L. · 2020 to 2025
–
National Institute of Child Health and Human Development R01HD031476National Institute of Child Health and Human Development R24HD050837NIAMS NIH HHS P30 AR058878NIAMS NIH HHS P30 AR061303NIAMS NIH HHS P30AR061303NICHD NIH HHS R01 HD031476NICHD NIH HHS R24 HD050837RRD VA I01 RX002462RRD VA IK6 RX003351U.S. Department of Veterans Affairs A9028R
6 · The paper itself

Abstract

Intramuscular pressure (IMP) shows promise for estimating individual muscle tension in vivo. However, previous pressure measurements show high variability during isometric contraction and poor correlation with tension during dynamic contraction. We hypothesized that enhanced sensor anchoring/orientation would improve tension estimation and thus developed a novel pressure sensor with a barbed housing. Sensors were inserted into the tibialis anterior (TA) of New Zealand White rabbits (N = 8) both parallel and perpendicular to the fiber orientation. We measured muscle stress and IMP during both isometric and dynamic contractions. Passive stress showed good agreement for both insertion directions across muscle lengths (ICC > 0.8). Active stress and IMP agreement were good (ICC = 0.87 ± 0.04) for perpendicular insertions but poor (ICC = 0.21 ± 0.22) for parallel insertions across both dynamic contractions and isometric contractions within the muscle's range of motion. These findings support use of IMP measurements to estimate muscle tension across a range of contraction conditions.

Indexed as

PressureAnimalsMuscle ContractionMuscle, SkeletalRabbitsStress, MechanicalDynamic contractionForce–length relationshipForce–velocity relationshipIsometric contraction

Identifiers

PMID33001290
PMCPMC8083084
OpenAlexW3090480112

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.