ArticleArchives of toxicology2021
Health effects after inhalation of micro- and nano-sized zinc oxide particles in human volunteers.
Article in Archives of toxicology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 70 citations in OpenAlex.
- Toxicity Evaluation of Nano-Sized Particles by Analysis of mtDNA Content and Expression Levels of Genes Required for mtDNA Maintenance: A Meta-Analysis of Pre-Clinical Studies.Antioxidants (Basel, Switzerland) · 2026Review
- Applicability of in vitro mouse lung epithelial cell responses for potency grouping and hazard identification of metal oxide nanoparticles: impact of form, size, surface area, and solubility on toxicity.Archives of toxicology · 2026Article
- Biological Safety Analysis of Nanoparticles: Exploring Toxicity, Mechanisms, and Safety Factors for Pharmaceuticals.International journal of nanomedicine · 2026Review
- A New Aerosol Respiratory Deposition Approach: Health Risks of Metals in Aerosols from Electronic Nicotine Delivery Systems and Heated Tobacco Products.Journal of aerosol science · 2026Article
- Welding fume exposure and respiratory innate immune activation: metal-rich particles, inflammatory biomarkers, and immune-informed occupational prevention.Frontiers in immunology · 2026Review
- The potential adverse human health effects of metal-containing nanoparticles: a scoping review.Journal of occupational medicine and toxicology (London, England) · 2025Review
- Sustainable antifungal potential of ZnO and MoSWorld journal of microbiology & biotechnology · 2025Article
- Cardiovascular Toxicity of Metal-Based Nanoparticles.International journal of molecular sciences · 2025Review
- Selective fluoride ion sensing using novel quinoline chemosensor insights into kinetics and molecular logic gate functions.Scientific reports · 2025Article
- Zinc fever in a painter and varnisher: a case report.Journal of medical case reports · 2024Article
- Re-evaluation of the occupational exposure limit for ZnO is warranted. Comments on 'Systemic inflammatory effects of zinc oxide particles: is a re-evaluation of exposure limits needed?' by Christian Monsé et al.Archives of toxicology · 2024Article
- Current research on ecotoxicity of metal-based nanoparticles: from exposure pathways, ecotoxicological effects to toxicity mechanisms.Frontiers in public health · 2024Review
- Immune response to zinc oxide inhalation in metal fume fever, and the possible role of IL-17f.Scientific reports · 2023Article
- Systemic inflammatory effects of zinc oxide particles: is a re-evaluation of exposure limits needed?Archives of toxicology · 2023Article
- Acute phase response following pulmonary exposure to soluble and insoluble metal oxide nanomaterials in mice.Particle and fibre toxicology · 2023Article
- Comparative study on the effects of micro- and nano-sized zinc oxide supplementation on zinc-deficient mice.Journal of veterinary science · 2023Article
- Metal Exposure-Related Welder's Pneumoconiosis and Lung Function: A Cross-Sectional Study in a Container Factory of China.International journal of environmental research and public health · 2022Article
- A proposed synergetic mechanism for metal fume fever involving ZnO and FeScientific reports · 2022Article
- Cell-biological effects of zinc oxide spheres and rods from the nano- to the microscale at sub-toxic levels.Cell biology and toxicology · 2021Article
- Colloidal Lignin Particles and Epoxies for Bio-Based, Durable, and Multiresistant Nanostructured Coatings.ACS applied materials & interfaces · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inhalation of ZnO particles can cause inflammation of the airways and metal fume fever. It is unclear if different sizes of the particles alter these effects. However, various studies report higher biological activity of other nano-sized particles compared to microparticles. No effects at all were observed after inhalation of micro- and nano-sized zinc oxide (ZnO) particle concentrations of 0.5 mg/m
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.