Evidence map›Paper›PMID 33001222›Full record

ReviewArchives of microbiology2021

Conditions of nisin production by Lactococcus lactis subsp. lactis and its main uses as a food preservative.

Simon Khelissa, Nour-Eddine Chihib, Adem Gharsallaoui

Abstract readReview
PubMed Publisher
In one paragraph

Review in Archives of microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 93 citations in OpenAlex.

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  6. Genetic Characterisation of Closely RelatedInternational journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Simon KhelissaUMR 8207-UMET-Unité Matériaux et Transformations, Univ Lille, CNRS, INRAE, Centrale Lille, 59000, Lille, France.
Nour-Eddine ChihibUMR 8207-UMET-Unité Matériaux et Transformations, Univ Lille, CNRS, INRAE, Centrale Lille, 59000, Lille, France.
Adem GharsallaouiLAGEPP UCBL CNRS 5007, Univ Lyon 1, 69622, Villeurbanne, France. adem.gharsallaoui@univ-lyon1.fr.ORCID http://orcid.org/0000-0002-6309-7757
Centre National de la Recherche Scientifique · FRUniversité Claude Bernard Lyon 1 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nisin is a small peptide produced by Lactococcus lactis ssp lactis that is currently industrially produced. This preservative is often used for growth prevention of pathogenic bacteria contaminating the food products. However, the use of nisin as a food preservative is limited by its low production during fermentation. This low production is mainly attributed to the multitude of parameters influencing the fermentation progress such as bacterial cells activity, growth medium composition (namely carbon and nitrogen sources), pH, ionic strength, temperature, and aeration. This review article focuses on the main parameters that affect nisin production by Lactococcus lactis bacteria. Moreover, nisin applications as a food preservative and the main strategies generally used are also discussed.

Indexed as

Food PreservativesCulture MediaFermentationIndustrial MicrobiologyLactococcus lactisNisinCulture MediaFood PreservativesNisinFermentationFood preservationLactic acid bacteria (LAB)Lactococcus lactisNisinProduction yields

Identifiers

PMID33001222
OpenAlexW3090226348

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.