Evidence map›Paper›PMID 33001028›Full record

ArticleeLife2020

Myogenin is an essential regulator of adult myofibre growth and muscle stem cell homeostasis.

Massimo Ganassi, Sara Badodi, Kees Wanders, Peter S Zammit, Simon M Hughes

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed, 1 pooled it
9.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 1 synthesis or guideline pooled it, 159 citations in OpenAlex.

  1. Pooled it
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  11. Trunk Muscle Differentiation and Growth in Vertebrates.Results and problems in cell differentiation · 2026
    Review
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38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Massimo GanassiRandall Centre for Cell and Molecular Biophysics, King's College London, London, United Kingdom.ORCID 0000-0003-3163-9707
Sara BadodiBlizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.ORCID 0000-0002-8407-8336
Kees WandersRandall Centre for Cell and Molecular Biophysics, King's College London, London, United Kingdom.ORCID 0000-0003-3209-9853
Peter S ZammitRandall Centre for Cell and Molecular Biophysics, King's College London, London, United Kingdom.ORCID 0000-0001-9562-3072
Simon M HughesRandall Centre for Cell and Molecular Biophysics, King's College London, London, United Kingdom.ORCID 0000-0001-8227-9225
King's College London · GBQueen Mary University of London · GB

Funding

Association Francaise contre les Myopathies AFM17865Association Française contre les Myopathies AFM17865FSH Society FSHS-82013-06FSH Society FSHS-82017-05Medical Research Council G1001029Medical Research Council MR/N021231/1Medical Research Council MR/P023215/1Medical Research Council MR/S002472/1Muscular Dystrophy UK RA3/3052
6 · The paper itself

Abstract

Growth and maintenance of skeletal muscle fibres depend on coordinated activation and return to quiescence of resident muscle stem cells (MuSCs). The transcription factor Myogenin (Myog) regulates myocyte fusion during development, but its role in adult myogenesis remains unclear. In contrast to mice,

Indexed as

AnimalsGene Knockout TechniquesHomeostasisMuscle, SkeletalMyofibrilsMyogeninStem CellsZebrafishZebrafish ProteinsMyogeninZebrafish Proteinsadultcell sizedevelopmental biologymuscle fibermyogeninnicheregenerative medicinestem cellstem cellszebrafish

Identifiers

PMID33001028
PMCPMC7599067
OpenAlexW3090434172

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.