Evidence map›Paper›PMID 33000914›Full record

ArticleJournal of the International AIDS Society2020

Retention of a cohort of men who have sex with men and transgender women at risk for and living with HIV in Abuja and Lagos, Nigeria: a longitudinal analysis.

Blessing O Kayode, Andrew Mitchell, Nicaise Ndembi, Afoke Kokogho, Habib O Ramadhani, Sylvia Adebajo, Merlin L Robb, Stefan D Baral, Julie A Ake, Manhattan E Charurat and 3 more

Abstract read
In one paragraph

Article in Journal of the International AIDS Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Blessing O KayodeInstitute of Human Virology Nigeria, Abuja, Nigeria.
Andrew MitchellInstitute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA.
Nicaise NdembiInstitute of Human Virology Nigeria, Abuja, Nigeria.
Afoke KokoghoHJF Medical Research International, Abuja, Nigeria.
Habib O RamadhaniInstitute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA.ORCID 0000-0001-9372-9359
Sylvia AdebajoMaryland Global Initiatives Corporation- A University of Maryland Baltimore Affiliate, Abuja, Nigeria.
Merlin L RobbU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Stefan D BaralDepartment of Epidemiology, Johns Hopkins School of Public Health, Baltimore, MD, USA.ORCID 0000-0002-5482-2419
Julie A AkeU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Manhattan E CharuratInstitute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA.
Trevor A CrowellU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.ORCID 0000-0001-5947-265X
Rebecca G NowakInstitute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA.ORCID 0000-0001-8404-4569
TRUST/RV368 Study Group

Funding

Validation of Stigma Metrics for Marginalized Men R01MH110358 · NIMH · JOHNS HOPKINS UNIVERSITY · PI BARAL, STEFAN DAVID · 2017 to 2021
$3.6M
Building TRUSTR01AI120913 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI CHARURAT, MANHATTAN E · 2015 to 2019
$3.3M
TRUSTR01MH099001 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI CHARURAT, MANHATTAN E · 2012 to 2014
$2.9M
Epidemiology Research Training for Public Health Impact in Nigeria (Epi-Nigeria)D43TW010051 · FIC · UNIVERSITY OF MARYLAND BALTIMORE · PI ABIMIKU, ALASH'LE G., CHARURAT, MANHATTAN E · 2016 to 2020
$1.5M
Role of anal microbiota, local cytokines and HIV in persistence of high-risk human papillomavirusK07CA225403 · NCI · UNIVERSITY OF MARYLAND BALTIMORE · PI NOWAK, REBECCA G. · 2018 to 2022
$677k
CDC HHS NU2GGH002099FIC NIH HHS D43 TW010051FIC NIH HHS D43TW010051NCI NIH HHS K07 CA225403NIAID NIH HHS R01 AI120913NIH HHS K07CA225403NIH HHS R01AI120913NIH HHS R01MH099001NIH HHS R01MH110358NIMH NIH HHS R01 MH099001NIMH NIH HHS R01 MH110358PEPFAR
6 · The paper itself

Abstract

introductionMen who have sex with men (MSM), and transgender women (TGW), face specific obstacles to retention in care, particularly in settings with stigmatization such as sub-Saharan Africa. We evaluated the impacts of HIV status and other factors on loss-to-follow-up (LTFU) and visit adherence among MSM and TGW in Abuja and Lagos, Nigeria.

methodsTRUST/RV368 is an open cohort that provides comprehensive and integrated prevention and treatment services for HIV and sexually transmitted infections (STIs) at community venues supportive of sexual and gender minorities. Recruitment began in March 2013 and participants were followed every three months for up to 18 months. LTFU was defined as not presenting for an expected visit in the past 180 days. Visit adherence was calculated as a rate of completed visits adjusted by the number of three-month intervals elapsed since enrolment. HIV and other factors predictive of LTFU and visit adherence were evaluated using Cox proportional hazards and Poisson regression models, respectively.

resultsA total of 1447 participants who completed enrolment evaluations over two visits as of November 2018 were included in these analyses. Their median age was 24 years (interquartile range [IQR]: 21 to 28) and 53% (n = 766) were living with HIV. LTFU occurred in 56% (n = 808) and visit adherence was 0.62 (95% confidence interval: 0.61 to 0.64) visits per three-month interval. Participants at risk and living with HIV had median follow-up times of 12 months (IQR: 6 to 22), and 21 months (IQR: 12 to 30), respectively (p < 0.01). After controlling for other factors, LTFU was less common among participants living with HIV or other STIs and more common among those who did not own a cell phone, sold sex and had never undergone HIV testing prior to enrolment. These factors had parallel associations with visit adherence.

conclusionsRetention was suboptimal in Nigerian clinics designed to serve MSM and TGW. Particularly high LTFU and low visit adherence among participants at risk for HIV could complicate deployment of HIV prevention interventions. Marketing the benefits of testing, improving access to cell phones and nurturing more trust with clients may improve retention among marginalized communities in Nigeria.

Indexed as

Homosexuality, MaleSexual and Gender MinoritiesTransgender PersonsTreatment Adherence and ComplianceAdultAftercareCohort StudiesFemaleHIV InfectionsHumansMaleNigeriaYoung AdultHIVretention in caresexual and gender minoritiessub-Saharan Africatreatment adherence and compliance

Identifiers

PMID33000914
PMCPMC7527765

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.