Evidence map›Paper›PMID 33000749›Full record

ArticleBlood transfusion = Trasfusione del sangue2021

Post-operative hypercoagulable whole blood profiles in patients undergoing open thoracotomy vs video-assisted thoracoscopic surgery.

Luca Spiezia, Marco Cuzzolin, Hernandez Elssy, Guido Di Gregorio, Elena Campello, Federico Rea, Andrea Zuin, Paolo Simioni

Open access · greenAbstract read
In one paragraph

Article in Blood transfusion = Trasfusione del sangue, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Luca SpieziaHaemorrhagic and Thrombotic Diseases Unit, Department of Medicine, Padua University Hospital, Padua, Italy.
Marco CuzzolinThoracic Surgery Division, Department of Cardiac, Thoracic and Vascular Sciences, Padua University Hospital, Padua, Italy.
Hernandez ElssyCardiothoracic Anaesthesia Unit, Department of Medicine, Padua University Hospital, Padua, Italy.
Guido Di GregorioCardiothoracic Anaesthesia Unit, Department of Medicine, Padua University Hospital, Padua, Italy.
Elena CampelloHaemorrhagic and Thrombotic Diseases Unit, Department of Medicine, Padua University Hospital, Padua, Italy.
Federico ReaThoracic Surgery Division, Department of Cardiac, Thoracic and Vascular Sciences, Padua University Hospital, Padua, Italy.
Andrea ZuinThoracic Surgery Division, Department of Cardiac, Thoracic and Vascular Sciences, Padua University Hospital, Padua, Italy.
Paolo SimioniHaemorrhagic and Thrombotic Diseases Unit, Department of Medicine, Padua University Hospital, Padua, Italy.
University of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients undergoing video-assisted thoracoscopic surgery (VATS) have a lower risk of thrombosis compared to those undergoing open thoracotomy (OT) which may be due to several post-operative factors such as early mobilisation, shorter hospital stays, lower transfusion rates and lower risk of infections. Whether the higher thrombotic risk after OT is also linked to a peri-operative hypercoagulable state is a matter of debate. We therefore conducted a case-control study to compare peri-operative coagulation profiles in patients with primary lung cancer undergoing VATS vs OT. MATERIALS AND

methodsAll consecutive patients undergoing VATS or OT for primary lung cancer at the Department of Thoracic Surgery of Padua University Hospital, Italy, between February and June 2018 were enrolled. Each patient provided a venous blood sample at least 30 min prior to surgical incision (T0) and 4±1 days after surgery (T1). Peri-operative coagulation profiles were assessed via traditional, viscoelastic whole blood (ROTEM

resultsWe enrolled 65 patients (males 43, females 22; mean age 65±13 years) of whom 35 (54%) underwent VATS and 30 (46%) underwent OT. Compared to healthy controls, the surgical group (VATS and OT patients) had a significantly shorter clot formation time and higher alpha angle and maximum clot firmness values, as well as increased mean platelet function. In the post-operative period, patients who underwent OT had a significantly shorter clot formation time, higher alpha angle and maximum clot firmness values and higher mean platelet function vs VATS patients. DISCUSSION: Whole blood ROTEM

Indexed as

AgedAged, 80 and overBlood CoagulationFemaleHumansLung NeoplasmsMaleMiddle AgedPostoperative ComplicationsThoracic Surgery, Video-AssistedThrombophilia

Identifiers

PMID33000749
PMCPMC7925226
OpenAlexW3091709063

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.