Evidence map›Paper›PMID 33000681›Full record

ArticleJournal of the American Heart Association2020

Risk Model for Decline in Activities of Daily Living Among Older Adults Hospitalized With Acute Myocardial Infarction: The SILVER-AMI Study.

Alexandra M Hajduk, John A Dodson, Terrence E Murphy, Sui Tsang, Mary Geda, Gregory M Ouellet, Thomas M Gill, John E Brush, Sarwat I Chaudhry

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Alexandra M HajdukDepartment of Internal Medicine Yale School of Medicine New Haven CT.
John A DodsonLeon H. Charney Division of Cardiology Department of Medicine New York University School of Medicine New York NY.
Terrence E MurphyDepartment of Internal Medicine Yale School of Medicine New Haven CT.
Sui TsangDepartment of Internal Medicine Yale School of Medicine New Haven CT.
Mary GedaDepartment of Internal Medicine Yale School of Medicine New Haven CT.
Gregory M OuelletDepartment of Internal Medicine Yale School of Medicine New Haven CT.
Thomas M GillDepartment of Internal Medicine Yale School of Medicine New Haven CT.
John E BrushSentara Healthcare and Eastern Virginia Medical School Norfolk VA.
Sarwat I ChaudhryDepartment of Internal Medicine Yale School of Medicine New Haven CT.
Yale University · USEastern Virginia Medical School · USMurphy Oil Corporation (United States) · USNew York University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale Study Support Suite (YES3): Dashboard and Web Portal Software Supporting Research Workflow through integrated, customizable REDCap External ModulesP30AG021342 · NIA · YALE UNIVERSITY · PI Albert C Shaw · 2002 to 2026
$37.9M
Risk Stratification in Older Persons with Acute Myocardial Infarction: SILVER-AMIR01HL115295 · NHLBI · YALE UNIVERSITY · PI CHAUDHRY, SARWAT I · 2012 to 2016
$11.3M
Yale Training Program in Geriatric Clinical Epidemiology and Aging-Related ResearchT32AG019134 · NIA · YALE UNIVERSITY · PI Terri R. Fried · 2001 to 2026
$7.5M
Geriatric impairments, risk of treatment-related harms, and shared decision-making among older adults with acute myocardial infarctionK23AG052463 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI DODSON, JOHN A · 2016 to 2019
$658k
ACADEMIC LEADERSHIP AWARD IN DISABILITY AND DISABLING DISORDERSK07AG043587 · NIA · YALE UNIVERSITY · PI GILL, THOMAS MICHAEL · 2013 to 2017
$645k
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS R01 HL115295NIA NIH HHS K07 AG043587NIA NIH HHS K23 AG052463NIA NIH HHS P30 AG021342NIA NIH HHS T32 AG019134
6 · The paper itself

Abstract

Background Functional decline (ie, a decrement in ability to perform everyday activities necessary to live independently) is common after acute myocardial infarction (AMI) and associated with poor long-term outcomes; yet, we do not have a tool to identify older AMI survivors at risk for this important patient-centered outcome. Methods and Results We used data from the prospective SILVER-AMI (Comprehensive Evaluation of Risk Factors in Older Patients With Acute Myocardial Infarction) study of 3041 patients with AMI, aged ≥75 years, recruited from 94 US hospitals. Participants were assessed during hospitalization and at 6 months to collect data on demographics, geriatric impairments, psychosocial factors, and activities of daily living. Clinical variables were abstracted from the medical record. Functional decline was defined as a decrement in ability to independently perform essential activities of daily living (ie, bathing, dressing, transferring, and ambulation) from baseline to 6 months postdischarge. The mean age of the sample was 82±5 years; 57% were men, 90% were White, and 13% reported activity of daily living decline at 6 months postdischarge. The model identified older age, longer hospital stay, mobility impairment during hospitalization, preadmission physical activity, and depression as risk factors for decline. Revascularization during AMI hospitalization and ability to walk a quarter mile before AMI were associated with decreased risk. Model discrimination (c=0.78) and calibration were good. Conclusions We identified a parsimonious model that predicts risk of activity of daily living decline among older patients with AMI. This tool may aid in identifying older patients with AMI who may benefit from restorative therapies to optimize function after AMI.

Indexed as

Activities of Daily LivingAgedAged, 80 and overHospitalizationHumansMaleModels, StatisticalMyocardial InfarctionProspective StudiesRisk AssessmentRisk Factorsacute myocardial infarctionpatient‐centered outcomesphysical function

Identifiers

PMID33000681
PMCPMC7792390
OpenAlexW3091380759

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.