Evidence map›Paper›PMID 33000560›Full record

SynthesisJournal of medical imaging and radiation oncology2020

Chest computed tomography (CT) features in children with reverse transcription-polymerase chain reaction (RT-PCR)-confirmed COVID-19: A systematic review.

Paolo Simoni, Alberto Bazzocchi, Grammatina Boitsios, Alessandro De Leucio, Marco Preziosi, Maria Pilar Aparisi Gómez

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of medical imaging and radiation oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. More on CT features in children with COVID-19.Journal of medical imaging and radiation oncology · 2022
    Article
  4. Article
  5. Review
  6. Emergent Pneumonia in Children.Frontiers in pediatrics · 2021
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Paolo SimoniPeadiatric Imaging Department, Queen Fabiola Children's University Hospital, Université Libre de Bruxelles, Bruxelles, Belgium.ORCID https://orcid.org/0000-0002-5957-0644
Alberto BazzocchiDiagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Grammatina BoitsiosPeadiatric Imaging Department, Queen Fabiola Children's University Hospital, Université Libre de Bruxelles, Bruxelles, Belgium.ORCID https://orcid.org/0000-0003-1575-9119
Alessandro De LeucioPeadiatric Imaging Department, Queen Fabiola Children's University Hospital, Université Libre de Bruxelles, Bruxelles, Belgium.
Marco PreziosiPeadiatric Imaging Department, Queen Fabiola Children's University Hospital, Université Libre de Bruxelles, Bruxelles, Belgium.
Maria Pilar Aparisi GómezDepartment of Radiology, Auckland City Hospital, Auckland, New Zealand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To describe the chest CT features reported in children with confirmed COVID-19 infection, published in English literature. A systematic review was completed on PubMed, Embase and Scopus databases on the 1st of June 2020 using the PICO strategy. The NIH Quality Assessment Tool was used to assess the quality of the selected articles. The systematic review was evaluated by Case Series Studies and the Preferred Reporting Items for a Systematic Review and Meta-analysis of Diagnostic Test Accuracy Studies (PRISMA). The extracted data were assessed and compared with those reported in the adult population. Seventy-two articles were retrieved from the database search and screened by the title, abstract and keywords. Eleven articles were deemed eligible for full-text assessment. Nine articles were included for the data extraction and in the final analysis. Chest CT features in children with COVID-19 differ from those in adults. 'Ground-grass opacities' (GGOs) are the most commonly described abnormalities, but closely followed by a combination of GGO and consolidation, not usual in adults. Children tend to have a more variable involvement than the subpleural and posterior and basal topography described in adults. Interlobular thickening and air bronchogram found in adults with COVID-19 are not frequent in children. Pulmonary embolism reported in up to 30% of adults has not been yet reported in children. Original articles describing chest CT features in children with COVID-19 in the English literature are limited to small populations of Chinese children. Chest CT imaging features are very diverse across the selected studies and globally different from those reported in adults. Data from children of different countries would provide a more comprehensive description of chest CT features in children with COVID-19.

Indexed as

BetacoronavirusChildClinical Laboratory TechniquesCoronavirus InfectionsCOVID-19COVID-19 TestingHumansLung DiseasesPandemicsPneumonia, ViralRadiography, ThoracicReverse Transcriptase Polymerase Chain ReactionSARS-CoV-2Tomography, X-Ray Computedchildrencomputerized tomographyCOVID-19epidemiologySARS-CoV-2systematic review

Identifiers

PMID33000560
PMCPMC7537213

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.