Evidence map›Paper›PMID 33000520›Full record

ArticleClinical physiology and functional imaging2021

Increased arterial stiffness in males with abdominal aortic aneurysm.

Ida Åström Malm, Rachel De Basso, Peter Blomstrand, Niclas Bjarnegård

Open access · hybridAbstract read
In one paragraph

Article in Clinical physiology and functional imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Status of diagnosis and therapy of abdominal aortic aneurysms.Frontiers in cardiovascular medicine · 2023
    Review
  13. Article
  14. Role of Extracellular Matrix and Inflammation in Abdominal Aortic Aneurysm.International journal of molecular sciences · 2022
    Review
  15. Wall shear stress and relative residence time as potential risk factors for abdominal aortic aneurysms in males: a 4D flow cardiovascular magnetic resonance case-control study.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2022
    Article
  16. Article
  17. Article
  18. Increased arterial stiffness in males with abdominal aortic aneurysm.Clinical physiology and functional imaging · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Ida Åström MalmDepartment of Natural Sciences and Biomedicine, School of Health and Welfare, Jönköping University, Jönköping, Sweden.ORCID https://orcid.org/0000-0001-5199-1623
Rachel De BassoDepartment of Natural Sciences and Biomedicine, School of Health and Welfare, Jönköping University, Jönköping, Sweden.
Peter BlomstrandDepartment of Natural Sciences and Biomedicine, School of Health and Welfare, Jönköping University, Jönköping, Sweden.
Niclas BjarnegårdDepartment of Diagnostics and Specialist Medicine, Faculty of Health, Medicine and Caring Sciences, University of Linköping, Linköping, Sweden.
Jönköping University · SELinköping University · SERyhov Hospital Jönköping · SE

Funding

Forskningsrådet i Sydöstra SverigeHjärt-Lungfonden
6 · The paper itself

Abstract

backgroundAbdominal aortic aneurysm (AAA), a localized dilatation of the abdominal aorta, has a prevalence of about 1.5%-3% among 65- to 70-year-old males in Europe. AAA confers an increased risk of developing major cardiovascular events in addition to the risk of aneurysm rupture. The aim of this study was to evaluate whether the arterial wall distensibility is altered in subjects with AAA.

methodsTwo hundred and eighty-four male subjects (182 with AAA and 102 controls) were enrolled in the study. Arterial wall distensibility was evaluated using non-invasive applanation tonometry to measure regional pulse wave velocity between the carotid and femoral arteries and the carotid and radial arteries. In addition, blood pressure was measured, and the pulse pressure waveform was analysed.

resultsHigher aortic augmentation index (25.1% versus 20.6%; p < .001) and higher aortic pulse wave velocity (12.3 m/s versus 10.9 m/s; p < .001) were demonstrated in the AAA cohort. The slightly higher arm pulse wave velocity in the AAA group (9.4 m/s versus 9.1 m/s; p < .05) was abolished after adjusting for mean arterial blood pressure.

conclusionsMales with AAA have decreased aortic wall distensibility and enhanced reflection waves in central aorta during systole. These results imply that increased arterial wall stiffness may be a contributing factor to the overall higher cardiovascular risk seen in patients with AAA.

Indexed as

Vascular StiffnessAgedAged, 80 and overAortic Aneurysm, AbdominalBlood Flow VelocityCarotid ArteriesFemoral ArteryHumansMaleManometryMiddle AgedPulse Wave AnalysisRadial Arteryarteriesblood pressurecardiovascular risk assessmentdistensibilitypulse wave velocity

Identifiers

PMID33000520
PMCPMC7756894
OpenAlexW3089652120

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.