Evidence map›Paper›PMID 33000423›Full record

ArticleNeuroscience bulletin2021

Distinct Effects of Social Stress on Working Memory in Obsessive-Compulsive Disorder.

Qianqian Li, Jun Yan, Jinmin Liao, Xiao Zhang, Lijun Liu, Xiaoyu Fu, Hao Yang Tan, Dai Zhang, Hao Yan

Open access · hybridAbstract read
In one paragraph

Article in Neuroscience bulletin, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. FreshFrontiers in pharmacology · 2023
    Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Qianqian Li *Peking University Sixth Hospital, Beijing, 100191, China.
Jun Yan *Peking University Sixth Hospital, Beijing, 100191, China.
Jinmin LiaoPeking University Sixth Hospital, Beijing, 100191, China.
Xiao ZhangPeking University Sixth Hospital, Beijing, 100191, China.ORCID http://orcid.org/0000-0002-2932-5875
Lijun LiuPeking University Sixth Hospital, Beijing, 100191, China.
Xiaoyu FuPeking University Sixth Hospital, Beijing, 100191, China.
Hao Yang TanLieber Institute for Brain Development, Baltimore, MD, 21205, USA.
Dai ZhangPeking University Sixth Hospital, Beijing, 100191, China. daizhang@bjmu.edu.cn.ORCID http://orcid.org/0000-0002-9162-7401
Hao Yan *Peking University Sixth Hospital, Beijing, 100191, China. hao_y@bjmu.edu.cn.ORCID http://orcid.org/0000-0003-0376-9037
Peking University · CNJohns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stress might exaggerate the compulsion and impair the working memory of patients with obsessive-compulsive disorder (OCD). This study evaluated the effect of stress on the cognitive neural processing of working memory in OCD and its clinical significance using a "number calculation working memory" task. Thirty-eight patients and 55 gender- and education-matched healthy controls were examined. Stress impaired the performance of the manipulation task in patients. Healthy controls showed less engagement of the medial prefrontal cortex and striatum during the task under stress versus less stress, which was absent in the patients with OCD. The diagnosis × stress interaction effect was significant in the right fusiform, supplementary motor area, precentral cortex and caudate. The failure of suppression of the medial prefrontal cortex and striatum and stress-related hyperactivation in the right fusiform, supplementary motor area, precentral cortex, and caudate might be an OCD-related psychopathological and neural response to stress.

Indexed as

Motor CortexObsessive-Compulsive DisorderHumansMagnetic Resonance ImagingMemory, Short-TermAcute stressFunctional magnetic resonance imagingObsessive-compulsive disorderWorking memory

Identifiers

PMID33000423
PMCPMC7811969
OpenAlexW3090747027

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.