Evidence map›Paper›PMID 33000415›Full record

ArticleChinese journal of integrative medicine2021

Effect and Safety of Tongyan Spray () on Hyoid Motion in Patients with Dysphagia after Ischemic Stroke.

Wen-Jie Hao, Bing-Jie Li, Xiao-Lei Wu, Zhen-Bo Chen, Xin Zhang, Han Yao, Wen-Yan Zhang, Xue-Gong Feng

Abstract read
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In one paragraph

Article in Chinese journal of integrative medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Wen-Jie HaoDepartment of Encephalopathy, Beijing Hospital of Integrated Traditional Chinese and Western Medicine, Beijing, 100039, China.
Bing-Jie LiDepartment of Neurology, China Rehabilitation Research Center, Beijing, 100068, China.
Xiao-Lei WuDepartment of Encephalopathy, Beijing Hospital of Integrated Traditional Chinese and Western Medicine, Beijing, 100039, China.
Zhen-Bo ChenDepartment of Radiology, China Rehabilitation Research Center, Beijing, 100068, China.
Xin ZhangThe 3rd Department of Neurorehabilitation, China Rehabilitation Research Center, Beijing, 100068, China.
Han YaoDepartment of Radiology, China Rehabilitation Research Center, Beijing, 100068, China.
Wen-Yan ZhangDepartment of Encephalopathy, Beijing Hospital of Integrated Traditional Chinese and Western Medicine, Beijing, 100039, China.
Xue-Gong FengDepartment of Encephalopathy, Beijing Hospital of Integrated Traditional Chinese and Western Medicine, Beijing, 100039, China. bjcwhfxg@sina.com.
China Rehabilitation Research Center · CNBeijing Hospital · CNBeijing Chang'an Integrated Traditional Chinese and Western Medicine Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo observe the effects and safety of Tongyan Spray () on the range and time of hyoid motion in patients with ischemic post-stroke dysphagia.

methodsSeventy-two patients with ischemic post-stroke dysphagia were selected and randomly assigned to a treatment group (36 cases) and a control group (36 cases) by a random number table from January 2013 to October 2014. All patients swallowed 4 kinds of barium meals with different traits respectively, and each patient underwent video fluoroscopy (VF) examination twice. In the treatment group, Tongyan Spray was sprayed to the pharynx on both sides and the middle part once respectively. The spray was applied 30 min before the second examination. Purified water at room temperature was used as placebo in the control group. The changes in the range and time of hyoid motion in both groups were observed before and after treatment.

resultsSix patients dropped out in each group, and 60 patients completed the study and were included in the final analysis. Significant improvement was observed in the range of superior hyoid excursion distance and the time of hyoid motion in the treatment group compared with the control group (P<0.05). There were no obvious adverse reactions observed in oral mucosa in both groups during the whole study.

conclusionTongyan Spray was an effective and safe medicine for improving swallowing function in patients with ischemic post-stroke dysphagia.

Indexed as

Brain IschemiaDeglutition DisordersIschemic StrokeDeglutitionHumansHyoid BoneChinese medicinedysphagiahyoid motionstrokeTongyan Sprayvideo fluoroscopy

Identifiers

PMID33000415
OpenAlexW3089934846

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.