Evidence map›Paper›PMID 33000332›Full record

Trial reportEuropean journal of applied physiology2021

HIIT is superior than MICT on cardiometabolic health during training and detraining.

Fernando Gripp, Roberto Carlos Nava, Ricardo Cardoso Cassilhas, Elizabethe Adriana Esteves, Caíque Olegário Diniz Magalhães, Marco Fabrício Dias-Peixoto, Flávio de Castro Magalhães, Fabiano Trigueiro Amorim

Abstract readComparative StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of applied physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Impact of exercise-based prehabilitation on cardiometabolic health in surgical patients with cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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  20. Preventing Metabolic Syndrome in Adolescents Through Exercise.Advances in experimental medicine and biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fernando GrippMulticenter Graduate Program in Physiological Sciences, Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil.
Roberto Carlos NavaDepartment of Health, Exercise, and Sports Sciences, Johnson Center B145 MSC04 2610, University of New Mexico, Albuquerque, NM, 87131-0001, USA.
Ricardo Cardoso CassilhasMulticenter Graduate Program in Physiological Sciences, Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil.
Elizabethe Adriana EstevesMulticenter Graduate Program in Physiological Sciences, Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil.
Caíque Olegário Diniz MagalhãesMulticenter Graduate Program in Physiological Sciences, Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil.
Marco Fabrício Dias-PeixotoMulticenter Graduate Program in Physiological Sciences, Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil.
Flávio de Castro MagalhãesMulticenter Graduate Program in Physiological Sciences, Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil.
Fabiano Trigueiro AmorimMulticenter Graduate Program in Physiological Sciences, Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil. amorim@unm.edu.ORCID http://orcid.org/0000-0003-2936-4484

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 447007/2014-9, 407975/2018-7Coordenação de Aperfeiçoamento de Pessoal de Nível Superior PNPD-2455/2011Fundação de Amparo à Pesquisa do Estado de Minas Gerais APQ-01915-13, APQ-01871-14, APQ-01727-18, APQ-01436-15, APQ-03058-16
6 · The paper itself

Abstract

purposeThis study investigated the cardiometabolic health of overweight/obese untrained individuals in response to 8 weeks of HIIT and MICT using a field approach, and to 4 weeks of training cessation (TC).

methodsTwenty-two subjects performed 8 weeks of moderate intensity continuous training (MICT-n = 11) or high-intensity interval training (HIIT-n = 11) (outdoor running), followed by 4 weeks of TC. Cardiorespiratory fitness, body composition, arterial blood pressure, glucose metabolism and blood lipids were measured pre-training (PRE), post-training (POST) and TC.

resultsHIIT improved eight indicators of cardiometabolic health ([Formula: see text], BMI, body fat, visceral fat, systolic blood pressure, total cholesterol, fasting glucose and triglycerides-p  < 0.05) while MICT only three ([Formula: see text], BMI, and visceral fat-p  < 0.05). After 4 weeks of TC, four positive adaptations from HIIT were negatively affected ( [Formula: see text], visceral fat, systolic blood pressure and total cholesterol-p  < 0.05) and three in the MICT group ([Formula: see text], BMI and visceral fat, p  < 0.05).

conclusionEight weeks of HIIT performed in a real-world setting promoted a greater number of positive adaptations in cardiometabolic health of individuals with overweight/obese compared to MICT. Most of the positive effects of the HIIT protocol were also found to be longer lasting and maintained after the suspension of high-intensity interval running for 4 weeks. Conversely, all positive effects of MICT protocols were reversed after TC.

Indexed as

Cardiorespiratory FitnessAdultBlood GlucoseBlood PressureBody CompositionEndurance TrainingFemaleHeart RateHigh-Intensity Interval TrainingHumansLipidsMaleMiddle AgedObesityOxygen ConsumptionBlood GlucoseLipidsBlood pressureCardiorespiratory fitnessDetrainingHigh-intensity interval trainingModerate-intensity continuous trainingObesity

Identifiers

PMID33000332

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.