Evidence map›Paper›PMID 33000320›Full record

ArticleJournal of materials science. Materials in medicine2020

3D construct of hydroxyapatite/zinc oxide/palladium nanocomposite scaffold for bone tissue engineering.

Fatemeh Heidari, Fahimeh Sadat Tabatabaei, Mehdi Razavi, Reza Bazargan Lari, Mina Tavangar, Georgios E Romanos, Daryoosh Vashaee, Lobat Tayebi

Abstract read
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In one paragraph

Article in Journal of materials science. Materials in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Finite element analysis andFrontiers in bioengineering and biotechnology · 2024
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fatemeh HeidariDepartment of Materials Engineering, School of Engineering, Yasouj University, Yasouj, 75918-74934, Iran. f.heidari@yu.ac.ir.ORCID http://orcid.org/0000-0002-8394-1222
Fahimeh Sadat TabatabaeiDepartment of Dental Biomaterials, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mehdi RazaviDepartment of Radiology, School of Medicine, Stanford University, Palo Alto, CA, 94304, USA.
Reza Bazargan LariDepartment of Materials Science and Engineering, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran.
Mina TavangarDepartment of Materials Engineering, School of Engineering, Yasouj University, Yasouj, 75918-74934, Iran.
Georgios E RomanosStony Brook University, School of Dental Medicine, Stony Brook, NY, 11794, USA.
Daryoosh VashaeeDepartment of Electrical and Computer Engineering, NC State University, Raleigh, NC, 27695, USA.
Lobat TayebiMarquette University School of Dentistry, Milwaukee, WI, 53233, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to produce and characterize Hydroxyapatite/Zinc Oxide/Palladium (HA/0.05 wt% ZnO/0.1 wt% Pd) nanocomposite scaffolds and study their mechanical and antibacterial properties, biocompatibility and bioactivity. The initial materials were developed using sol-gel and precipitation methods. Scaffolds were characterized using atomic absorption analysis (AA), scanning electron microcopy (SEM), energy dispersive spectroscopy (EDS) and transmission electron microscopy (TEM), atomic force microscopy (AFM) and Brunauer-EmmeS-Teller (BET) method. Furthermore, the bioactivity of scaffolds in simulated body fluid (SBF) and the interaction of dental pulp stem cells (DPSCs) with the nanocomposite scaffolds were assessed. Our results showed that the HA/ZnO/Pd (H1), HA/ZnO/Pd coated by 0.125 g chitosan (H2) and HA/ZnO/Pd coated by 0.25 g chitosan (H3) scaffolds possess higher compressive strength and toughness and lower microhardness and density compared to the pure HA (H0) scaffolds. Immersion of samples in SBF showed the deposition of apatite on the surface of the scaffolds. The biocompatibility assay indicated lower cell proliferation on the H1, H2 and H3 in comparison to the H0. The antibacterial results obtained show a significant impact by loading Pd/ZnO on HA in the deactivation of microorganisms in vitro.

Indexed as

Bone and BonesAnti-Bacterial AgentsBiocompatible MaterialsBody FluidsBone SubstitutesCell ProliferationChitosanCompressive StrengthDurapatiteHumansInhibitory Concentration 50In Vitro TechniquesMaterials TestingMicroscopy, Atomic ForceMicroscopy, Electron, ScanningNanocompositesAnti-Bacterial AgentsBiocompatible MaterialsBone SubstitutesChitosanDurapatiteNitritesPalladiumpalladium oxidePowdersZincZinc Oxide

Identifiers

PMID33000320

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.