Evidence map›Paper›PMID 33000301›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2021

Multi-parametric arterial spin labeling and diffusion-weighted imaging in differentiation of metastatic from reactive lymph nodes in head and neck squamous cell carcinoma.

Ahmed Abdel Khalek Abdel Razek, Eman Helmy

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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ahmed Abdel Khalek Abdel RazekDepartment of Diagnostic Radiology, Mansoura Faculty of Medicine, Mansoura, 13551, Egypt. arazek@mans.edu.eg.ORCID http://orcid.org/0000-0002-9613-5932
Eman HelmyDepartment of Diagnostic Radiology, Mansoura Faculty of Medicine, Mansoura, 13551, Egypt.
Mansoura University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess arterial spin labeling (ASL) and diffusion-weighted imaging (DWI) in the differentiation of metastatic from reactive lymph nodes (LNs) in head and neck squamous cell carcinoma (HNSCC). MATERIALS AND

methodsRetrospective analysis of 113 LNs in 43 patients with HNSCC underwent ASL and DWI of the neck. The tumor blood flow (TBF) and apparent diffusion coefficient (ADC) of the cervical LNs were calculated. The final diagnosis of metastatic (n = 82) and reactive (n = 31) was proved with the pathological examination.

resultsThe TBF of metastatic LNs (58.8 ± 10.2, 58.6 ± 8.5 mL/100 g/min) was significantly higher (p = 0.001) than the reactive LNs (23.2 ± 10.3, 28.2 ± 16.7 mL/100 g/min) for both observers, respectively. The ADC of metastatic LN (1.12 ± 0.07, 1.21 ± 0.07 × 10

conclusionCombined TBF and ADC are non-invasive imaging parameters that can play a role in differentiation metastatic from reactive LNs in patients with HNSCC.

Indexed as

Diffusion Magnetic Resonance ImagingHead and Neck NeoplasmsCell DifferentiationHumansLymphatic MetastasisLymph NodesRetrospective StudiesSensitivity and SpecificitySpin LabelsSquamous Cell Carcinoma of Head and NeckSpin LabelsArterial spinCancerDiffusionHeadMR imagingNeckPerfusion

Identifiers

PMID33000301
OpenAlexW3091228219

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.