Evidence map›Paper›PMID 33000193›Full record

ArticleInternational journal of molecular medicine2020

[Comment] COVID‑19 vaccine safety.

Ronald N Kostoff, Michael B Briggs, Alan L Porter, Demetrios A Spandidos, Aristidis Tsatsakis

Abstract read
In one paragraph

Article in International journal of molecular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. The long COVID research literature.Frontiers in research metrics and analytics · 2023
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Role of vaccine in fighting the variants of COVID-19.Chaos, solitons, and fractals · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Factors associated with side effects of COVID-19 vaccine in Indonesia.Clinical and experimental vaccine research · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ronald N KostoffSchool of Public Policy, Georgia Institute of Technology, Gainesville, VA 20155, USA.
Michael B BriggsIndependent Consultant, Roscommon, MI 48653, USA.
Alan L PorterSchool of Public Policy, Georgia Institute of Technology, Atlanta, GA 30332, USA.
Demetrios A SpandidosLaboratory of Clinical Virology, Medical School, University of Crete, 70013 Heraklion, Greece.
Aristidis TsatsakisLaboratory of Toxicology, Medical School, University of Crete, 70013 Heraklion, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In response to the SARS‑CoV‑2 outbreak, and the resulting COVID‑19 pandemic, a global competition to develop an anti‑COVID‑19 vaccine has ensued. The targeted time frame for initial vaccine deployment is late 2020. The present article examines whether short‑term, mid‑term, and long‑term vaccine safety can be achieved under such an accelerated schedule, given the myriad vaccine‑induced mechanisms that have demonstrated adverse effects based on previous clinical trials and laboratory research. It presents scientific evidence of potential pitfalls associated with eliminating critical phase II and III clinical trials, and concludes that there is no substitute currently available for long‑term human clinical trials to ensure long‑term human safety.

Indexed as

AnimalsClinical Trials as TopicCost-Benefit AnalysisCOVID-19COVID-19 VaccinesHumansCOVID-19 Vaccines

Identifiers

PMID33000193
PMCPMC7521561

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.