Evidence map›Paper›PMID 32999909›Full record

ArticleGE Portuguese journal of gastroenterology2020

Azathioprine-Induced Acute Submandibular Sialadenitis in a Crohn's Disease Patient.

Joana Inês Alves da Silva, Cidalina Caetano, Isabel Pedroto

Open access · diamondAbstract readCase Reports
In one paragraph

Article in GE Portuguese journal of gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Joana Inês Alves da SilvaGastroenterology, Centro Hospitalar Universitário do Porto, Porto, Portugal.
Cidalina CaetanoGastroenterology, Centro Hospitalar Universitário do Porto, Porto, Portugal.
Isabel PedrotoGastroenterology, Centro Hospitalar Universitário do Porto, Porto, Portugal.
Centro Hospitalar do Porto · PTUniversidade do Porto · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAzathioprine (AZA) is a widely used immunosuppressive drug in inflammatory bowel disease (IBD). The occurrence of adverse effects (AEs) is a major downside in the use of this drug, leading to treatment withdrawal in a variable proportion of patients. CASE PRESENTATION: We report the case of a Crohn's disease patient who developed sialadenitis as an AE to AZA. DISCUSSION AND

conclusionTo our knowledge this AE has been reported only once in the literature. Sialadenitis is a common disorder and refers to inflammation of a salivary gland. It has many causes, such as bacterial and viral infections, ductal obstruction, and drugs. There are several AEs related to this drug, categorized as dose-dependent and dose-independent. Their knowledge is essential for therapeutic management in IBD, which is already challenging, requiring an individualized approach.

Indexed as

Adverse effectAzathioprineCrohn's diseaseSialadenitis

Identifiers

PMID32999909
PMCPMC7506223
OpenAlexW3000037831

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.