Evidence map›Paper›PMID 32999840›Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2020

Chemical Manipulation of Abscisic Acid Signaling: A New Approach to Abiotic and Biotic Stress Management in Agriculture.

Kamalani Achala H Hewage, Jing-Fang Yang, Di Wang, Ge-Fei Hao, Guang-Fu Yang, Jian-Kang Zhu

Open access · goldAbstract readReview
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
15.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 174 citations in OpenAlex.

  1. Plant strategies against herbivorous insects.Journal of integrative plant biology · 2026
    Review
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  6. Review
  7. Article
  8. Research on the Hormonomics of ThreeAntioxidants (Basel, Switzerland) · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Abscisic Acid Can Play a Dual Role in thePlants (Basel, Switzerland) · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Review

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Kamalani Achala H HewageKey Laboratory of Pesticide & Chemical Biology Ministry of Education College of Chemistry Central China Normal University Wuhan 430079 P. R. China.
Jing-Fang YangKey Laboratory of Pesticide & Chemical Biology Ministry of Education College of Chemistry Central China Normal University Wuhan 430079 P. R. China.
Di WangKey Laboratory of Pesticide & Chemical Biology Ministry of Education College of Chemistry Central China Normal University Wuhan 430079 P. R. China.
Ge-Fei HaoKey Laboratory of Pesticide & Chemical Biology Ministry of Education College of Chemistry Central China Normal University Wuhan 430079 P. R. China.ORCID https://orcid.org/0000-0002-3507-1664
Guang-Fu YangKey Laboratory of Pesticide & Chemical Biology Ministry of Education College of Chemistry Central China Normal University Wuhan 430079 P. R. China.
Jian-Kang ZhuShanghai Center for Plant Stress Biology and CAS Center of Excellence in Molecular Plant Sciences Chinese Academy of Sciences Shanghai 20032 P. R. China.
Central China Normal University · CNChinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The phytohormone abscisic acid (ABA) is the best-known stress signaling molecule in plants. ABA protects sessile land plants from biotic and abiotic stresses. The conserved pyrabactin resistance/pyrabactin resistance-like/regulatory component of ABA receptors (PYR/PYL/RCAR) perceives ABA and triggers a cascade of signaling events. A thorough knowledge of the sequential steps of ABA signaling will be necessary for the development of chemicals that control plant stress responses. The core components of the ABA signaling pathway have been identified with adequate characterization. The information available concerning ABA biosynthesis, transport, perception, and metabolism has enabled detailed functional studies on how the protective ability of ABA in plants might be modified to increase plant resistance to stress. Some of the significant contributions to chemical manipulation include ABA biosynthesis inhibitors, and ABA receptor agonists and antagonists. Chemical manipulation of key control points in ABA signaling is important for abiotic and biotic stress management in agriculture. However, a comprehensive review of the current knowledge of chemical manipulation of ABA signaling is lacking. Here, a thorough analysis of recent reports on small-molecule modulation of ABA signaling is provided. The challenges and prospects in the chemical manipulation of ABA signaling for the development of ABA-based agrochemicals are also discussed.

Indexed as

ABA signalingagonistsantagonistschemical manipulationplant stress

Identifiers

PMID32999840
PMCPMC7509701
OpenAlexW3048327486

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.