ReviewThe World Allergy Organization journal2020
Oral CorticoSteroid sparing with biologics in severe asthma: A remark of the
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Review in The World Allergy Organization journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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33citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
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Who cites it
33 citing papers in PubMed, 51 citations in OpenAlex.
- Review
- Longitudinal observation of severe asthma comorbidities and oral corticosteroids use from SANI and ISAR registries.The World Allergy Organization journal · 2026Article
- Challenges in Evaluating Clinical Remission in Severe Asthma: Insights from the Mayo Clinic.Advances in therapy · 2026Article
- Glucocorticoid-induced adrenal insufficiency: physiological dose tapering promotes recovery.Endocrine connections · 2026Article
- Review
- Patient response and remission in respiratory disease: Special focus on severe asthma and chronic obstructive pulmonary disease.The Journal of international medical research · 2025Review
- Retrospective Cohort Study of Elderly Users of Single- or Multiple-Inhaler Triple Therapy for the Treatment of Asthma in the USA.Pulmonary therapy · 2025Article
- Costs of Oral Corticosteroid Use in Patients with Severe Asthma With/Without Chronic Rhinosinusitis with Nasal Polyps: Data from the Italian SANI Registry.Advances in therapy · 2025Article
- Connections and Unmet Needs: Severe Asthma Biologics and Osteoporosis.Biomedicines · 2025Review
- Use of oral corticosteroids in patients with asthma: how far is clinical practice from the guidelines? Results from surveys of patients and doctors.Frontiers in allergy · 2025Article
- Perceptions of oral corticosteroid use for children with asthma in a survey of US caregivers.Frontiers in pediatrics · 2025Article
- RIAIT (Italian Registry of Allergen Immunotherapy): Protocol for a New Tool in a New Vision of Disease-Modifying Therapy for Allergists.Journal of personalized medicine · 2024Article
- Profiling severe asthma: Any relevance for age? An analysis from Severe Asthma Network Italy (SANI) cohort.The World Allergy Organization journal · 2024Article
- Safety of Biological Therapies for Severe Asthma: An Analysis of Suspected Adverse Reactions Reported in the WHO Pharmacovigilance Database.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2024Article
- Real-World Effectiveness of Biologics in Patients With Severe Asthma: Analysis of the KoSAR.Allergy, asthma & immunology research · 2024Article
- Evaluation of Clinical Remission in Best-Performing Severe Asthmatic Patients Treated for Three Years with Mepolizumab.Biomedicines · 2024Article
- Management of patients with chronic rhinosinusitis with nasal polyps (CRSwNP): Results from a survey among allergists and clinical immunologists of the North-west and Center Italy Inter-Regional Sections of SIAAIC and otorhinolaryngologists of National IAR.The World Allergy Organization journal · 2024Article
- Clinical remission and control in severe asthma: agreements and disagreements.Drugs in context · 2024Review
- Very long-term data on patients with severe eosinophilic asthma treated with mepolizumab: a case series.Drugs in context · 2024Article
- Asthma severity: the patient's point of view.European clinical respiratory journal · 2024Article
Corrections and comments
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Authors and funding
61 authors at 20 institutions in 1 country.
Giorgio Walter CanonicaPersonalized Medicine, Asthma & Allergy, Humanitas Clinical and Research Center, IRCCS, Rozzano, MI, Italy.
Francesco BlasiRespiratory Unit and Adult Cystic Fibrosis Center, And Department of Pathophysiology and Transplantation, Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, University of Milan, Italy.
Pierluigi PaggiaroDepartment of Surgery, Medicine, Molecular Biology and Critical Care, University of Pisa, Italy.
Gianenrico SennaDepartment of Medicine, Allergy Unit Asthma Center, University of Verona, Italy.
Giovanni PassalacquaAllergy and Respiratory Diseases, IRCCS Policlinico San Martino, University of Genoa, Italy.
Antonio SpanevelloUniversity of Insubria, ICS Maugeri, IRCCS, Varese, Italy.
Stefano AlibertiRespiratory Unit and Adult Cystic Fibrosis Center, And Department of Pathophysiology and Transplantation, Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, University of Milan, Italy.
Diego BagnascoAllergy and Respiratory Diseases, IRCCS Policlinico San Martino, University of Genoa, Italy.
Marco BonaviaRespiratory Rehabilitation, ASL3, Genoa, Italy.
Matteo BoniniFondazione Policlinico Universitario A. Gemelli, IRCCS Catholic University of Rome, Italy.
Luisa BrussinoAllergy and Clinical Immunology, University of Turin & AO Mauriziano, Turin, Italy.
Caterina BuccaAllergy and Clinical Immunology, University of Turin & AO Mauriziano, Turin, Italy.
Maria F CaiaffaDepartment of Medical Sciences and Surgery, School and Chair of Allergology and Clinical Immunology, University of Foggia, Italy.
Cecilia CalabreseDepartment of Translational Medical Sciences, University of Campania "L. Vanvitelli", Naples, Italy.
Gianna CamiciottoliDeptartment of Experimental and Clinical Biomedical Sciences "Mario Serio", Respiratory Unit, Careggi University Hospital, Florence, Italy.
Marco CaminatiDepartment of Medicine, Allergy Unit Asthma Center, University of Verona, Italy.
Giovanna E CarpagnanoRespiratory Medicine Section, Policlinico of Bari, Department of Basic Medical Science, Neuroscience and Sense Organs, University of Bari Aldo Moro, Bari, Italy.
Cristiano CarusoAllergy Unit, Fondazione Policlinico A. Gemelli, IRCCS, Rome, Italy.
Stefano CentanniDepartment of Health Sciences, University of Milan, Respiratory Unit, ASST Santi Paolo e Carlo, Milan, Italy.
Maria E ConteRespiratory Unit, Presidio Ospedaliero of Pordenone, Italy.
Angelo G CorsicoDivision of Respiratory Diseases, IRCCS Policlinico San Matteo, Foundation and Department of Internal Medicine and Therapeutics, University of Pavia, Italy.
Lorenzo CosmiDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Maria T CostantinoAllergy and Clinical Immunology Unit, Department of Medicine, "Carlo Poma" Hospital, Mantova, Italy.
Nunzio CrimiDivision of Pneumology and Allergology, Policlinico, University of Catania, Italy.
Simona D'AlòAllergology Unit, AV3 ASUR Marche, Hospital Civitanova Marche, Macerata, Italy.
Maria D'AmatoRespiratory Department, Division of Respiratory Diseases "Federico II" University, AO Dei Colli, Naples, Italy.
Stefano Del GiaccoDepartment of Medical Sciences and Public Health, University of Cagliari, Italy.
Alessandro FarsiSOS of Allergology and Clinical Immunology, Azienda USL Toscana Centro, Prato, Italy.
Elisabetta FaveroSevere Asthma Multidisciplinary Outpatient Clinic, Vittorio Veneto Hospital, Treviso, Italy.
Maria P Foschino BarbaroSection of Respiratory Diseases, Medical and Surgical Sciences Department, University of Foggia, Italy.
Gabriella GuarnieriDepartment of Cardiac-Thoracic-Vascular Sciences and Public Health, University of Padua, Italy.
Giuseppe GuidaAllergy and Pneumology Unit, A.O. S. Croce & Carle, Cuneo, Italy.
Manuela LatorreDepartment of Surgery, Medicine, Molecular Biology and Critical Care, University of Pisa, Italy.
Salvatore Lo CiceroDepartment of Pneumology, Niguarda Hospital, Milan, Italy.
Carlo LombardiDepartmental Unit of Allergology and Pneumology, Hospital Institute Fondazione Poliambulanza, Brescia, Italy.
Luigi MacchiaDepartment of Emergency and Organ Transplantation, School and Chair of Allergology and Clinical Immunology, University of Bari Aldo Moro, Bari, Italy.
Francesco MazzaRespiratory Unit, Presidio Ospedaliero of Pordenone, Italy.
Francesco MenzellaPneumology Unit, Santa Maria Nuova Hospital, Azienda USL di Reggio Emilia IRCCS, Italy.
Manlio MilanesePulmonology Unit, ASL2 Savonese, Pietra Ligure, Savona, Italy.
Marcello MontagniUOC Allergology Department, Piacenza, Italy.
Paolo MontuschiDepartment of Pharmacology, Faculty of Medicine Catholic, University of the Sacred Heart Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Eleonora NuceraCatholic University S. Heart, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Roberta ParenteDepartment of Medicine, Division of Allergy and Clinical Immunology, University of Salerno, Italy.
Vincenzo PatellaAllergology and Clinical Immunology Unit, Department of Medical Science, "Santa Maria Della Speranza" Hospital of Battipaglia, Salerno, Italy.
Girolamo PelaiaDepartment of Medical and Surgical Sciences, Section of Respiratory Diseases, University Magna Graecia, Catanzaro, Italy.
Laura PiniDepartment of Clinical and Experimental Sciences, University of Brescia, Spedali Civili, Brescia, Italy.
Francesca PuggioniPersonalized Medicine, Asthma & Allergy, Humanitas Clinical and Research Center, IRCCS, Rozzano, MI, Italy.
Luisa RicciardiAllergy and Clinical Immunology Unit, University Hospital "G. Martino", Department of Clinical and Experimental Medicine, University of Messina, Italy.
Fabio L M RicciardoloDepartment of Clinical and Biological Sciences, University of Turin, San Luigi Hospital, Orbassano, Turin, Italy.
Luca RicheldiFondazione Policlinico Universitario A. Gemelli, IRCCS Catholic University of Rome, Italy.
Erminia RidoloDepartment of Medicine and Surgery, University of Parma, Italy.
Giovanni RollaAllergy and Clinical Immunology, University of Turin & AO Mauriziano, Turin, Italy.
Pierachille SantusDepartment of Clinical and Biomedical Sciences, University of Milan, Respiratory Diseases, Sacco University Hospital, ASST Fatebenefratelli-Sacco, Milan, Italy.
Nicola ScichiloneDivision of Respiratory Diseases, Department of Promoting Health, Maternal-Infant. Excellence and Internal and Specialized Medicine (Promise) G. D'Alessandro, University of Palermo, Palermo, Italy.
Giuseppe SpadaroDepartment of Internal Medicine, Clinical Immunology, Clinical Pathology and Infectious Diseases, Azienda Ospedaliera Universitaria Federico II, Naples, Italy.
Andrea VianelloDivision of Respiratory Pathophysiology, Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Italy.
Vittorio VivianoAllergology, Pneumology and Respiratory Department 42 PTA Biondo-Regional Center for Allergy Prevention and Anaphylactic Shock, Palermo, Italy.
Mona R YacoubUnit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Maria C ZappaPulmonology Department, Sandro Pertini Hospital, Rome, Italy.
Enrico HefflerPersonalized Medicine, Asthma & Allergy, Humanitas Clinical and Research Center, IRCCS, Rozzano, MI, Italy.
SANI (Severe Asthma Network Italy)
Humanitas University · ITAgostino Gemelli University Polyclinic · ITA. O. Ordine Mauriziano di Torino · ITFederico II University Hospital · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITPresidio Ospedaliero · ITUniversity of Bari Aldo Moro · ITUniversity of Foggia · ITUniversity of Genoa · ITUniversity of Milan · ITUniversity of Padua · ITUniversity of Pisa · ITUniversity of Turin · ITUniversity of Verona · ITASST Fatebenefratelli Sacco · ITAzienda Ospedaliera Carlo Poma · ITAzienda Ospedaliero-Universitaria Careggi · ITAzienda Sanitaria Locale N. 2 Savonese · ITAzienda Sanitaria Ospedaliera S.Croce e Carle Cuneo · ITAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · IT
Funding
No grant is acknowledged in the PubMed record.
Abstract
According to the data derived from several national and international registries, including SANI (Severe Asthma Network Italy), and considering the strong impact that frequent or regular use of oral corticosteroid has on quality of life (QoL) of severe asthmatics, as well as on the costs for managing corticosteroid-related diseases, oral corticosteroid sparing up to withdrawal should be considered a primary outcome in the management of severe asthma. New biologics have clearly demonstrated that this effect is possible, with concomitant reduction in the rate of exacerbations and in symptom control. Then, there is no reason for using so frequently oral corticosteroid before having explored all alternatives currently available for a large part of severe asthmatics.
Indexed as
BiologicsCRSwNP, chronic rhinosinusitis with nasal polyposisEMA, European Medicines AgencyFDA, Food & Drug AdministrationFEV1, forced expiratory volume in the 1st secondGINA, Global Initiative for AsthmaGRADE, Grading of Recommendations Assessment, Development and EvaluationISAR, International Severe Asthma RegistryOCSs, Oral CorticoSteroidsOral corticosteroidsReal-lifeRegistrRW, Real WorldSANI, Severe Asthma Network in ItalySARP, Severe Asthma Research ProgramSA, severe asthmaSevere asthmaSHARP, Severe Heterogeneous Asthma Research collaboration, Patient-centred
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