ArticleCase reports in ophthalmology
A Human Amniotic Membrane Plug to Treat Persistent Macular Hole.
Article in Case reports in ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 9 citations in OpenAlex.
- Surgical Outcomes of Epiretinal Human Amniotic Membrane Transplantation for Refractory Macular Holes.Journal of clinical medicine · 2026Article
- Human amniotic membrane graft with viscodissection and intraoperative OCT for macular hole repair.American journal of ophthalmology case reports · 2025Article
- Biological ultrathin amniotic membrane flap to close refractory macular holes associated with high myopia.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Article
- Safety and efficacy of human amniotic membrane plug transplantation in cases of macular hole. A scoping review.International journal of retina and vitreous · 2024Article
- Human Amniotic Membrane: A Seal for Complex Retinal Detachments.Turkish journal of ophthalmology · 2024Article
- The developments in amniotic membrane transplantation in glaucoma and vitreoretinal procedures.International ophthalmology · 2023Review
- Anatomical, functional outcomes, and complications of human amniotic membrane graft for macular hole: A systematic review.Taiwan journal of ophthalmologyReview
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The human amniotic membrane (hAM) has lately demonstrated interesting potential in its retinal applications. Nowadays, the treatment of persistent macular holes is still a challenge. In this paper, we present a case of a hAM plug used to treat a persistent macular hole, with the purpose of highlighting the critical issues of this new surgical procedure. We performed a 23-G pars plana vitrectomy and inserted a hAM plug (diameter of 1.5 mm) under the neuroretinal margins of the hole (diameter of 657 μm). A complete ophthalmic examination with the assessment of best-corrected visual acuity (logMAR units, ETDRS letter score) and optical coherence tomography (OCT) scans were collected at 1, 4, 6, and 10 weeks after surgery. Visual acuity changed from logMAR 1.0 (1) preoperatively to logMAR 1.0 (2), 1.0 (4), 0.9 (9), and 0.9 (10) at 1, 4, 6, and 10 weeks of follow-up, respectively. The 1 week postoperative OCT did not show neuroretinal adhesion over the plug, but the following visits showed reattachment of the margins with partial neuroretinal ingrowth. These findings suggest that the correct adaptation of the size of the hAM plug to the macular hole is essential to allow the anatomical closure of the hole and potential functional results.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.