Evidence map›Paper›PMID 32999361›Full record

ArticleScientific reports2020

Rajyoga meditation induces grey matter volume changes in regions that process reward and happiness.

M G Ramesh Babu, Rajagopal Kadavigere, Prakashini Koteshwara, Brijesh Sathian, Kiranmai S Rai

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

M G Ramesh BabuDepartment of Physiology, Melaka Manipal Medical College, Manipal Academy of Higher Education [MAHE], Manipal, Karnataka, 576104, India.
Rajagopal KadavigereDepartment of Radiodiagnosis and Imaging, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.
Prakashini KoteshwaraDepartment of Radiodiagnosis and Imaging, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.
Brijesh SathianDeputy Chair for Research, Geriatrics and Long Term Care Department, Rumailah Hospital, PO Box-3050, Doha, Qatar.
Kiranmai S RaiDepartment of Physiology, Melaka Manipal Medical College, Manipal Academy of Higher Education [MAHE], Manipal, Karnataka, 576104, India. kiranmai.rai@manipal.edu.
Manipal Academy of Higher Education · INKasturba Medical College, Manipal · INMelaka Manipal Medical College · INQatar Airways (Qatar) · QA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studies provide evidence that practicing meditation enhances neural plasticity in reward processing areas of brain. No studies till date, provide evidence of such changes in Rajyoga meditation (RM) practitioners. The present study aimed to identify grey matter volume (GMV) changes in reward processing areas of brain and its association with happiness scores in RM practitioners compared to non-meditators. Structural MRI of selected participants matched for age, gender and handedness (n = 40/group) were analyzed using voxel-based morphometric method and Oxford Happiness Questionnaire (OHQ) scores were correlated. Significant increase in OHQ happiness scores were observed in RM practitioners compared to non-meditators. Whereas, a trend towards significance was observed in more experienced RM practitioners, on correlating OHQ scores with hours of meditation experience. Additionally, in RM practitioners, higher GMV were observed in reward processing centers-right superior frontal gyrus, left inferior orbitofrontal cortex (OFC) and bilateral precuneus. Multiple regression analysis showed significant association between OHQ scores of RM practitioners and reward processing regions right superior frontal gyrus, left middle OFC, right insula and left anterior cingulate cortex. Further, with increasing hours of RM practice, a significant positive association was observed in bilateral ventral pallidum. These findings indicate that RM practice enhances GMV in reward processing regions associated with happiness.

Indexed as

HappinessRewardAdultBrainBrain MappingFemaleGray MatterHumansMagnetic Resonance ImagingMaleMeditationMiddle AgedNeuronal PlasticityOrgan Size

Identifiers

PMID32999361
PMCPMC7528075
OpenAlexW3091342958

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.