Evidence map›Paper›PMID 32999239›Full record

ArticleInternal medicine (Tokyo, Japan)2021

Anti-glomerular Basement Membrane Glomerulonephritis During the First Trimester of Pregnancy.

Hirayasu Kai, Joichi Usui, Takashi Tawara, Mayumi Takahashi-Kobayashi, Ryota Ishii, Ryoya Tsunoda, Akiko Fujita, Kei Nagai, Shuzo Kaneko, Naoki Morito and 3 more

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hirayasu KaiDivision of Clinical Medicine, Department of Nephrology, Faculty of Medicine, University of Tsukuba, Japan.
Joichi UsuiDivision of Clinical Medicine, Department of Nephrology, Faculty of Medicine, University of Tsukuba, Japan.
Takashi TawaraDivision of Clinical Medicine, Department of Nephrology, Faculty of Medicine, University of Tsukuba, Japan.
Mayumi Takahashi-KobayashiDivision of Clinical Medicine, Department of Nephrology, Faculty of Medicine, University of Tsukuba, Japan.
Ryota IshiiDivision of Clinical Medicine, Department of Nephrology, Faculty of Medicine, University of Tsukuba, Japan.
Ryoya TsunodaDivision of Clinical Medicine, Department of Nephrology, Faculty of Medicine, University of Tsukuba, Japan.
Akiko FujitaDivision of Clinical Medicine, Department of Nephrology, Faculty of Medicine, University of Tsukuba, Japan.
Kei NagaiDivision of Clinical Medicine, Department of Nephrology, Faculty of Medicine, University of Tsukuba, Japan.
Shuzo KanekoDivision of Clinical Medicine, Department of Nephrology, Faculty of Medicine, University of Tsukuba, Japan.
Naoki MoritoDivision of Clinical Medicine, Department of Nephrology, Faculty of Medicine, University of Tsukuba, Japan.
Chie SaitoDivision of Clinical Medicine, Department of Nephrology, Faculty of Medicine, University of Tsukuba, Japan.
Hiromi HamadaDivision of Clinical Medicine, Department of Obstetrics & Gynecology, Faculty of Medicine, University of Tsukuba, Japan.
Kunihiro YamagataDivision of Clinical Medicine, Department of Nephrology, Faculty of Medicine, University of Tsukuba, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 28-year-old woman was admitted during the eighth week of her pregnancy because her clinical course was consistent with rapid progressive glomerulonephritis (RPGN). Anti-glomerular basement membrane antibody (anti-GBM Ab) and myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA) were positive, and the anti-GBM Ab titer being extremely high. She was treated with hemodialysis, plasma exchange and prednisolone. She survived the illness; however, neither the fetus nor her kidney function could be rescued. She had human leukocyte antigen (HLA)-DRB1*1502:01, which differs from the DRB1*1501 associated with anti-GBM GN. When patients have particular symptoms, we should check the urine and serum creatinine to exclude RPGN, even in cases of pregnancy.

Indexed as

GlomerulonephritisPeroxidaseAdultAntibodies, Antineutrophil CytoplasmicAutoantibodiesFemaleHumansKidney GlomerulusPregnancyPregnancy Trimester, FirstAntibodies, Antineutrophil CytoplasmicAutoantibodiesPeroxidase1st trimester of pregnancyanti-glomerular basement membrane glomerulonephritis (anti-GBM GN)HLA-DRB1*1502:01plasma exchange (PE)rapid progressive glomerulonephritis (RPGN)

Identifiers

PMID32999239
PMCPMC7990629

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.