Evidence map›Paper›PMID 32999225›Full record

ArticleInternal medicine (Tokyo, Japan)2021

Distribution of Deep Gray Matter Lesions on Magnetic Resonance Imaging in Lymphomatosis Cerebri.

Zen Kobayashi, Sawako Sakai, Sakiko Itaya, Yoshiyuki Numasawa, Kiyobumi Ota, Miho Akaza, Yasuhiro Ueda, Shinichi Ogawa, Shoichiro Ishihara, Hiroyuki Tomimitsu and 1 more

Abstract read
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Lymphomatosis cerebri: a rare diffuse leukoencephalopathy you should never miss.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zen KobayashiDepartment of Neurology, JA Toride Medical Center, Japan.
Sawako SakaiDepartment of Neurology, JA Toride Medical Center, Japan.
Sakiko ItayaDepartment of Neurology, Kanto Central Hospital, Japan.
Yoshiyuki NumasawaAozora Clinic, Japan.
Kiyobumi OtaDepartment of Neurology, Nakatsu Municipal Hospital, Japan.
Miho AkazaDepartment of Neurology and Neurological Science, Tokyo Medical and Dental University, Japan.
Yasuhiro UedaDepartment of Neurosurgery, JA Toride Medical Center, Japan.
Shinichi OgawaDepartment of Hematology, JA Toride Medical Center, Japan.
Shoichiro IshiharaDepartment of Neurology, JA Toride Medical Center, Japan.
Hiroyuki TomimitsuDepartment of Neurology, JA Toride Medical Center, Japan.
Shuzo ShintaniDepartment of Neurology, JA Toride Medical Center, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein report the distribution of gray matter lesions on magnetic resonance imaging (MRI) in two patients with lymphomatosis cerebri (LC). In our patients, the fluid-attenuated inversion recovery sequence of brain MRI demonstrated a bilateral and diffuse high signal intensity, not only in the white matter but also in the thalamus, globus pallidus, putamen, and hippocampus. Among the deep gray matter, the caudate head and putamen (striatum) were relatively spared when compared with the globus pallidus, thalamus, and hippocampus. Interestingly, we found seven previous reports of similar MRI findings, with relative sparing of the striatum, in patients with LC. This finding may be characteristic of LC and help facilitate its diagnosis. Further investigations of a larger number of LC patients are necessary to confirm these findings.

Indexed as

Gray MatterMagnetic Resonance ImagingBrainGlobus PallidusHumansPutamencaudate headdeep gray matterlymphomatosis cerebriputamenstriatum

Identifiers

PMID32999225
PMCPMC7946510

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.