Genetic Control of Neonatal Immune Tolerance to an Exogenous Retrovirus.
Emily Cullum, Stanislav Dikiy, Helen A Beilinson, Melissa Kane, Alessandra Veinbachs, Vera M Beilinson, Lisa K Denzin, Alexander Chervonsky, Tatyana Golovkina
Article in Journal of virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
1 citing paper in PubMed, 3 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
9 authors at 2 institutions in 1 country.
Emily CullumCommittee on Immunology, University of Chicago, Chicago, Illinois, USA.
Stanislav DikiyDepartment of Microbiology, University of Chicago, Chicago, Illinois, USA.
Helen A BeilinsonDepartment of Microbiology, University of Chicago, Chicago, Illinois, USA.
Melissa KaneDepartment of Microbiology, University of Chicago, Chicago, Illinois, USA.
Alessandra VeinbachsDepartment of Microbiology, University of Chicago, Chicago, Illinois, USA.
Vera M BeilinsonDepartment of Microbiology, University of Chicago, Chicago, Illinois, USA.
Lisa K DenzinChild Health Institute of NJ, Department of Pediatrics, Rutgers Robert Wood Johnson Medical School, The State University of NJ, New Brunswick, New Jersey, USA.
Alexander ChervonskyCommittee on Immunology, University of Chicago, Chicago, Illinois, USA.
Tatyana GolovkinaCommittee on Immunology, University of Chicago, Chicago, Illinois, USA tgolovki@bsd.uchicago.edu.ORCID 0000-0002-2924-6747
University of Chicago · USRutgers, The State University of New Jersey · US
Funding
VIRAL ONCOLOGY CORE FACILITYP30CA014599 · NCI · UNIVERSITY OF CHICAGO · PI CHIEN-MIN KAO · 1985 to 2026
$122.1M
MEDICAL SCIENTIST TRAININGT32GM007281 · NIGMS · UNIVERSITY OF CHICAGO · PI CLARK, MARCUS RAMSAY · 1985 to 2022
$32.1M
ULTRASTRUCTURE AND CYTOMORPHOLOGY COREP30DK042086 · NIDDK · UNIVERSITY OF CHICAGO · PI CHANG, EUGENE B · 1990 to 2025
$29.8M
Re-Engineering Translational Research at the University of ChicagoUL1TR000430 · NCATS · UNIVERSITY OF CHICAGO · PI SOLWAY, JULIAN · 2012 to 2016
$20.2M
New retroviral restriction factorR01AI117535 · NIAID · UNIVERSITY OF CHICAGO · PI GOLOVKINA, TATYANA V · 2016 to 2020
$3.2M
A neonatal mouse model to study retrovirus-specific humoral responsesR01AI142844 · NIAID · UNIVERSITY OF CHICAGO · PI GOLOVKINA, TATYANA V · 2018 to 2022
$2.5M
Probing short and long term consequences of Small and Large Bowel Microbiota Transplants on Host Physiology: Implications for the development of future live biotherapeuticsR01DK138072 · NIDDK · UNIVERSITY OF CHICAGO · PI EUGENE B CHANG, Kristina Brooke Martinez-Guryn · 2024 to 2026
$2.1M
New retroviral restriction factorR56AI117535 · NIAID · UNIVERSITY OF CHICAGO · PI GOLOVKINA, TATYANA V · 2021 to 2021
Viruses, including retroviruses, can be passed from mothers to their progeny during birth and breastfeeding. It is assumed that newborns may develop immune tolerance to milk-transmitted pathogens similarly to food antigens. I/LnJ mice are uniquely resistant to retroviruses acquired as newborns or as adults as they produce virus-neutralizing antibodies (Abs). A loss-of-function allele of
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Genetic Control of Neonatal Immune Tolerance to an Exogenous Retrovirus. · full record | OpenQuestion