Evidence map›Paper›PMID 32999018›Full record

ArticleJournal of virology2020

Herpes Simplex Virus 1 (HSV-1) 0ΔNLS Live-Attenuated Vaccine Protects against Ocular HSV-1 Infection in the Absence of Neutralizing Antibody in HSV-1 gB T Cell Receptor-Specific Transgenic Mice.

Grzegorz B Gmyrek, Adrian Filiberti, Micaela Montgomery, Alisha Chitrakar, Derek J Royer, Daniel J J Carr

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Grzegorz B GmyrekDepartment of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.
Adrian FilibertiDepartment of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.
Micaela MontgomeryDepartment of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.
Alisha ChitrakarDepartment of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.
Derek J RoyerDepartment of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.
Daniel J J CarrDepartment of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA Dan-Carr@ouhsc.edu.ORCID 0000-0003-1954-2478
University of Oklahoma Health Sciences Center · US

Funding

Proteomics CoreP20GM103447 · NIGMS · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI David W Dyer · 2012 to 2026
$60.2M
P30-CENTER CORE GRANT FOR VISION RESEARCHP30EY021725 · NEI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Michelle C Callegan, MICHAEL H ELLIOTT · 2011 to 2026
$10.5M
The Neuroimmunology of Viral InfectionR01AI053108 · NIAID · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI CARR, DANIEL J · 2003 to 2022
$5.8M
NEI NIH HHS P30 EY021725NIAID NIH HHS R01 AI053108NIGMS NIH HHS P20 GM103447
6 · The paper itself

Abstract

The contribution of T cell and antibody responses following vaccination in resistance to herpes simplex virus 1 (HSV-1) infection continues to be rigorously investigated. In the present article, we explore the contribution of CD8

Indexed as

AnimalsAntibodies, NeutralizingAntibodies, ViralCD8-Positive T-LymphocytesCorneaFemaleHerpes SimplexHerpes Simplex Virus VaccinesHerpesvirus 1, HumanImmunizationMaleMiceMice, Inbred C57BLMice, TransgenicReceptors, Antigen, T-CellTrigeminal GanglionAntibodies, NeutralizingAntibodies, Viralglycoprotein B, SimplexvirusHerpes Simplex Virus VaccinesReceptors, Antigen, T-CellVaccines, AttenuatedViral Envelope ProteinsCD8 T celleyeHSV-1interferonmetabolismtransgenic micevaccines

Identifiers

PMID32999018
PMCPMC7925190
OpenAlexW3088755065

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.