Evidence map›Paper›PMID 32998984›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2020

Non-Cell-Autonomous Activity of the Hemidesmosomal Protein BP180/Collagen XVII in Granulopoiesis in Humanized NC16A Mice.

Lin Lin, Bin-Jin Hwang, Ning Li, Paul Googe, Luis A Diaz, Ed Miao, Barbara Vilen, Nancy E Thomas, Jenny Ting, Zhi Liu

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. BP180/Collagen XVII: A Molecular View.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Lin LinDepartment of Dermatology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.
Bin-Jin HwangDepartment of Dermatology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.
Ning LiDepartment of Dermatology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.
Paul GoogeDepartment of Dermatology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.ORCID 0000-0002-9185-3548
Luis A DiazDepartment of Dermatology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.ORCID 0000-0002-7308-292X
Ed MiaoDepartment of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599; and.ORCID 0000-0001-7295-3490
Barbara VilenDepartment of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599; and.ORCID 0000-0003-0014-0022
Nancy E ThomasDepartment of Dermatology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.
Jenny TingDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.ORCID 0000-0002-7846-0395
Zhi LiuDepartment of Dermatology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599; zhi_liu@med.unc.edu.
University of North Carolina at Chapel Hill · US

Funding

Sex Differences in Methylome Alterations and Mutational Burden in Early Stage MelanomaP01CA206980 · NCI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI BERWICK, MARIANNE, THOMAS, NANCY E. · 2017 to 2022
$10.1M
Identification of Lethal Melanomas at the Time of DiagnosisR01CA233524 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ANTON-CULVER, HODA A, BEGG, COLIN B · 2020 to 2024
$4.5M
IMMUNOPATHOGENESIS OF BULLOUS PEMPHIGOIDR01AI040768 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LIU, ZHI · 2001 to 2016
$4.1M
Eosinophils in Bullous PemphigoidR01AR070276 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LIU, ZHI · 2017 to 2021
$1.9M
Inflammasome-gasdermin axis in bullous pemphigoidR01AR072694 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LIU, ZHI, MIAO, EDWARD A · 2018 to 2022
$1.9M
The Mechanism of IVIG Action in PemphigusR01AI061430 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LIU, ZHI · 2004 to 2006
$999k
NCI NIH HHS P01 CA206980NCI NIH HHS R01 CA233524NIAID NIH HHS R01 AI040768NIAID NIH HHS R01 AI061430NIAMS NIH HHS R01 AR070276NIAMS NIH HHS R01 AR072694
6 · The paper itself

Abstract

BP180 (also termed type XVII collagen) is a hemidesmosomal protein and plays a critical role in cell-cell matrix adhesion in the skin; however, its other biological functions are largely unclear. In this study, we generated a BP180 functional-deficient mouse strain by deleting its extracellular domain of humanized NC16A (termed

Indexed as

AnimalsAutoantigensBone MarrowCell DifferentiationCollagen Type XVIIDisease Models, AnimalGranulocyte Colony-Stimulating FactorHumansHyperplasiaLeukopoiesisMesenchymal Stem CellsMiceMice, TransgenicNeutrophilsNF-kappa BNon-Fibrillar CollagensAutoantigensCollagen Type XVIIGranulocyte Colony-Stimulating FactorNF-kappa BNon-Fibrillar Collagens

Identifiers

PMID32998984
PMCPMC7658030
OpenAlexW3091099912

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.