SynthesisWorld journal of emergency surgery : WJES2020
Global changes in mortality rates in polytrauma patients admitted to the ICU-a systematic review.
Synthesis in World journal of emergency surgery : WJES, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06732752 (Prospective Validation of the New Trauma Score), which is not on this map. Cited by 94 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prospective Validation of the New Trauma Score (NTS) for Superior Prediction of Mortality Compared to the Revised Trauma Score
Who cites it
94 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Significant other reported outcome measures within European cohorts of severely injured patients: A systematic review.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Pooled it
- Neutrophil cell surface receptor dynamics following trauma: a systematic review.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025Pooled it
- Early versus late tracheostomy in people with multiple trauma.The Cochrane database of systematic reviews · 2025Pooled it
- Blood transfusion strategies for major bleeding in trauma.The Cochrane database of systematic reviews · 2025Pooled it
- Substantial heterogeneity in trauma triage tool characteristic operationalization for identification of major trauma: a hybrid systematic review.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025Pooled it
- Accuracy of pre-hospital triage tools for major trauma: a systematic review with meta-analysis and net clinical benefit.World journal of emergency surgery : WJES · 2021Pooled it
- Early Restrictive vs Liberal Oxygen for Trauma Patients: The TRAUMOX2 Randomized Clinical Trial.JAMA · 2025Trial
- 25-Year experience with adult polytraumatized patients in a European level 1 trauma center: polytrauma between 1995 and 2019. What has changed? A retrospective cohort study.Archives of orthopaedic and trauma surgery · 2023Trial
- Prehospital Transfusion With Red Blood Cells and Fresh Plasma in Helicopter Emergency Medical Services.Acta anaesthesiologica Scandinavica · 2026Article
- Blunt versus penetrating trauma: differences in early physiology, coagulopathy, and outcomes in a Scandinavian trauma centre.Scandinavian journal of trauma, resuscitation and emergency medicine · 2026Observational
- Prognostic Value of APACHE II and RTS in Predicting ICU Mortality Among Multitrauma Patients: A Single-Center Study from Turkey.Journal of clinical medicine · 2026Article
- Epidemiology of major work-related injuries in Abu Dhabi, United Arab Emirates: a 10-year retrospective study.BMJ open · 2026Article
- Hyperspectral imaging for objective microcirculatory assessment in trauma patients.Scientific reports · 2026Observational
- Multiple organ dysfunction syndrome: molecular mechanisms and therapeutic strategies.Signal transduction and targeted therapy · 2026Review
- Clinical evaluation of the SeptiScore biomarker for the diagnosis of healthcare-associated infections in critically ill trauma patients: a multicenter derivation and validation cohort study.BMC anesthesiology · 2026Observational
- Older age and post-traumatic organ failure a TraumaRegister DGUEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
- Graph Neural Networks for Realistic Bleeding Prediction in Surgical Simulators.Journal of imaging informatics in medicine · 2026Article
- Spices to Combat Sepsis: Curcumin and Piperine Combination Increases Survival and Modulates Immune Response in a Murine Two-Hit Trauma Model.Shock (Augusta, Ga.) · 2026Article
- Early Prediction and Prognostic Value of Chronic Critical Illness and Persistent Inflammation, Immunosuppression, and Catabolism Syndrome in Patients with Severe Acute Pancreatitis: A Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- Time-dependent microbial colonisation of temporary external fixations: a prospective descriptive study.Journal of orthopaedic surgery and research · 2026Article
34 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMany factors of trauma care have changed in the last decades. This review investigated the effect of these changes on global all-cause and cause-specific mortality in polytrauma patients admitted to the intensive care unit (ICU). Moreover, changes in trauma mechanism over time and differences between continents were analyzed. MAIN BODY: A systematic review of literature on all-cause mortality in polytrauma patients admitted to ICU was conducted. All-cause and cause-specific mortality rates were extracted as well as trauma mechanism of each patient. Poisson regression analysis was used to model time trends in all-cause and cause-specific mortality. Thirty studies, which reported mortality rates for 82,272 patients, were included and showed a decrease of 1.8% (95% CI 1.6-2.0%) in all-cause mortality per year since 1966. The relative contribution of brain injury-related death has increased over the years, whereas the relative contribution of death due to multiple organ dysfunction syndrome (MODS), acute respiratory distress syndrome, and sepsis decreased. MODS was the most common cause of death in North America, and brain-related death was the most common in Asia, South America, and Europe. Penetrating trauma was most often reported in North America and Asia.
conclusionsAll-cause mortality in polytrauma patients admitted to the ICU has decreased over the last decades. A shift from MODS to brain-related death was observed. Geographical differences in cause-specific mortality were present, which may provide region-specific learning possibilities resulting in improvement of global trauma care.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.