ArticleBMC nephrology2020
The association between chronic kidney disease and tuberculosis; a comparative cohort study in England.
Article in BMC nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Risk of Tuberculosis Disease in People With Chronic Kidney Disease Without Kidney Failure: A Systematic Review and Meta-analysis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Pooled it
- Risk for development of active tuberculosis in patients with chronic airway disease-a systematic review of evidence.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2022Pooled it
- Tuberculosis comorbidities, multimorbidity and mortality amongst adults in South Africa: A prospective cohort study nested in a trial.PLOS global public health · 2026Article
- Association between iron deficiency anemia and the risk of new-onset tuberculosis infection: a matched cohort analysis.Frontiers in nutrition · 2026Article
- The Role of Type I Interferons in Tuberculosis and in Tuberculosis-Risk-Associated Comorbidities.Infectious disease reports · 2025Review
- Screening for latent tuberculosis infection in patients with chronic kidney disease: a review of evidence and current practice in the UK.Clinical kidney journal · 2025Review
- Real-world safety and effectiveness of adalimumab in patients with pyoderma gangrenosum: Interim analysis of a post-marketing observational study in Japan.The Journal of dermatology · 2025Observational
- Factors associated with time to relapse in pulmonary tuberculosis patients using penalized Cox models.BMC research notes · 2024Article
- Non-communicable comorbidities in pulmonary tuberculosis and healthcare utilization: a cross-sectional study of 2021 Indonesian national health insurance data.Archives of public health = Archives belges de sante publique · 2024Article
- Tuberculosis survivors and the risk of cardiovascular disease: analysis using a nationwide survey in Korea.Frontiers in cardiovascular medicine · 2024Article
- Prevalence of Latent Tuberculosis Infection among Patients Undergoing Regular Hemodialysis in Disenfranchised Communities: A Multicenter Study during COVID-19 Pandemic.Medicina (Kaunas, Lithuania) · 2023Article
- Risk factors of latent tuberculosis among chronic kidney disease with routine haemodialysis patients.Journal of clinical tuberculosis and other mycobacterial diseases · 2022Article
- Clinical characteristics and chest computed tomography findings related to the infectivity of pulmonary tuberculosis.BMC infectious diseases · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundPeople with end-stage kidney disease have an increased risk of active tuberculosis (TB). Previous systematic reviews have demonstrated that patients with chronic kidney disease (CKD) have increased risk of severe community-acquired infections. We investigated the association between CKD (prior to renal replacement therapy) and incidence of TB in UK General Practice.
methodsUsing the UK Clinical Practice Research Datalink, 242,349 patients with CKD (stages 3-5) (estimated glomerular filtration rate < 60 mL/min/1.73 m
resultsThe incidence of TB was higher amongst patients with CKD compared to those without CKD: 14.63 and 9.89 cases per 100,000 person-years. After adjusting for age, gender, ethnicity, socio-economic status, diabetes and COPD, the association between CKD and TB remained (adjusted rate ratio [RR] 1.42, 95% confidence interval [CI] 1.01-1.85). The association may be stronger amongst those from non-white ethnic minorities (adjusted RR 2.83, 95%CI 1.32-6.03, p-value for interaction with ethnicity = 0.061). Amongst those with CKD stages 3-5, there was no evidence of a trend with CKD severity.
conclusionsCKD is associated with an increased risk of TB diagnosis in a UK General Practice cohort. This group of patients should be considered for testing and treating for latent TB.
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